This review focuses on the biology of T helper 17 (Th17) and regulatory T (Treg) cells and
their role in inflammatory diseases, such as rheumatoid arthritis. Th17 cells represent a pro …

Inflammatory bowel disease (IBD) includes Crohn's disease (CD) and ulcerative colitis (UC).
The exact cause of IBD remains unknown. Available evidence suggests that an abnormal …

Recent studies have demonstrated that thymus-derived naturally occurring CD4+ Foxp3+
regulatory T cells (Tregs) in human and mouse may be unstable and dysfunctional in the …

Abstract Naturally occurring Foxp3+ CD25+ CD4+ regulatory T (TREG) cells maintain
immunological self-tolerance and prevent a variety of autoimmune diseases, including …

Regulatory T cells (Tregs) prevent autoimmunity and tissue damage resulting from
excessive or unnecessary immune activation through their suppressive function. While their …

Abstract The imbalance of Th17/Treg cell populations has been suggested to be involved in
the regulation of rheumatoid arthritis (RA) pathogenesis; however, the mechanism behind …

Regulatory T (Treg) cells play a vital role in the prevention of autoimmunity and the
maintenance of self‐tolerance, but these cells also have an active role in inhibiting immune …

Regulatory T cells (Tregs) suppress exuberant immune system activation and promote
immunologic tolerance. Because Tregs modulate both innate and adaptive immunity, the …

Myasthenia Gravis (MG) is a paradigm of organ-specific autoimmune disease (AID). It is
mediated by antibodies that target the neuromuscular junction. The purpose of this review is …

ABSTRACT Identification of CD4+ Foxp3+ Tregs and Th17 modified the historical Th1–Th2
paradigm. Currently, the Th17–Tregs dichotomy provides a dominant conceptual framework …