The cardiovascular system plays a key role in sepsis, and septic myocardial depression is a
common finding associated with increased morbidity and mortality. Myocardial depression …

Sepsis is among the most common reasons for admission to ICUs throughout the world, and
it is believed to be the third most common cause of death in the United States. The …

Importance Severe sepsis and septic shock are major causes of mortality in intensive care
unit (ICU) patients. It is unknown whether progress has been made in decreasing their …

Background The Surviving Sepsis Campaign recommends targeting a mean arterial
pressure of at least 65 mm Hg during initial resuscitation of patients with septic shock …

Introduction Despite recent advances in the management of septic shock, mortality remains
unacceptably high. Earlier initiation of key therapies including appropriate antimicrobials …

Phaeochromocytoma crisis is an endocrine emergency associated with significant mortality.
There is little published guidance on the management of phaeochromocytoma crisis. This …

Morbidity and mortality from sepsis remains unacceptably high. Large variability in clinical
practice, plus the increasing awareness that certain processes of care associated with …

The medical literature and the lay press often report substantial changes in the incidence or
mortality of different diseases, including accounts of both large improvements in survival and …

Background Several case series and small randomized controlled trials suggest that
therapeutic plasma exchange (TPE) improves coagulation, hemodynamics and possibly …

Objective: The frequency, risk factors, and mortality rates of serious adverse events
associated with the use of vasopressin and norepinephrine are not clear. The objectives of …