Digit patterning is controlled by a Bmp-Sox9-Wnt Turing network modulated by morphogen gradients

J Raspopovic, L Marcon, L Russo, J Sharpe - Science, 2014 - science.org
During limb development, digits emerge from the undifferentiated mesenchymal tissue that
constitutes the limb bud. It has been proposed that this process is controlled by a self …

[图书][B] Stochastic processes in cell biology

PC Bressloff - 2014 - Springer
One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

[HTML][HTML] Direct discontinuous Galerkin method for nonlinear reaction–diffusion systems in pattern formation

R Zhang, X Yu, J Zhu, AFD Loula - Applied Mathematical Modelling, 2014 - Elsevier
Nonlinear reaction–diffusion systems are often employed in mathematical modeling for
pattern formation. Most of the work to date has been concerned within one-dimensional or …

An efficient, nonlinear stability analysis for detecting pattern formation in reaction diffusion systems

WR Holmes - Bulletin of mathematical biology, 2014 - Springer
Reaction diffusion systems are often used to study pattern formation in biological systems.
However, most methods for understanding their behavior are challenging and can rarely be …

Stochastic Turing patterns: analysis of compartment-based approaches

Y Cao, R Erban - Bulletin of mathematical biology, 2014 - Springer
Turing patterns can be observed in reaction-diffusion systems where chemical species have
different diffusion constants. In recent years, several studies investigated the effects of noise …

Discrete and continuous models for tissue growth and shrinkage

CA Yates - Journal of Theoretical Biology, 2014 - Elsevier
The incorporation of domain growth into stochastic models of biological processes is of
increasing interest to mathematical modellers and biologists alike. In many situations …

Predicting the spatiotemporal dynamics of hair follicle patterns in the developing mouse

CW Cheng, B Niu, M Warren… - Proceedings of the …, 2014 - National Acad Sciences
Reaction–diffusion models have been used as a paradigm for describing the de novo
emergence of biological patterns such as stripes and spots. In many organisms, these initial …

Stability on time-dependent domains

E Knobloch, R Krechetnikov - Journal of Nonlinear Science, 2014 - Springer
We explore the key differences in the stability picture between extended systems on time-
fixed and time-dependent spatial domains. As a paradigm, we take the complex Swift …

Feedback, receptor clustering, and receptor restriction to single cells yield large Turing spaces for ligand-receptor-based Turing models

T Kurics, D Menshykau, D Iber - Physical Review E, 2014 - APS
Turing mechanisms can yield a large variety of patterns from noisy, homogenous initial
conditions and have been proposed as patterning mechanism for many developmental …

Mathematical modelling of digit specification by a sonic hedgehog gradient

TE Woolley, RE Baker, C Tickle… - Developmental …, 2014 - Wiley Online Library
Background: The three chick wing digits represent a classical example of a pattern specified
by a morphogen gradient. Here we have investigated whether a mathematical model of a …