Agile delivery of protein therapeutics to CNS
X Yi, DS Manickam, A Brynskikh… - Journal of Controlled …, 2014 - Elsevier
A variety of therapeutic proteins have shown potential to treat central nervous system (CNS)
disorders. Challenge to deliver these protein molecules to the brain is well known. Proteins …
disorders. Challenge to deliver these protein molecules to the brain is well known. Proteins …
Cell-penetrating peptide-based intelligent liposomal systems for enhanced drug delivery
Liposomes are widely used as drug delivery systems and several liposome-based
nanomedicines have been approved for clinical use. Cell penetrating peptides (CPPs) have …
nanomedicines have been approved for clinical use. Cell penetrating peptides (CPPs) have …
Angiopep-2 and activatable cell penetrating peptide dual modified nanoparticles for enhanced tumor targeting and penetrating
Delivering chemotherapeutics by nanoparticles into tumor was influenced by at least two
factors: specific targeting and highly efficient penetrating of the nanoparticles. In this study …
factors: specific targeting and highly efficient penetrating of the nanoparticles. In this study …
Perspectives and challenges of Cell-Penetrating peptides in effective siRNA delivery
Over the last two decades, hundreds of cell penetrating peptides (CPPs) have been
intensively developed as drug and nucleic acid delivery vectors. In many cases, however …
intensively developed as drug and nucleic acid delivery vectors. In many cases, however …