Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period

I Jones, PS Chandra, P Dazzan, LM Howard - The Lancet, 2014 - thelancet.com
The perinatal period is associated with an increased risk of severe mental disorders. We
summarise the evidence regarding the epidemiology, risk factors, and treatment of severe …

Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways

GK Azad, RS Tomar - Molecular biology reports, 2014 - Springer
Ebselen, an organoselenium compound, mimics glutathione peroxidase activity. It is a
multifunctional compound, which catalyzes several essential reactions for the protection of …

Lithium for prevention of mood episodes in bipolar disorders: systematic review and meta-analysis

E Severus, MJ Taylor, C Sauer, A Pfennig… - International journal of …, 2014 - Springer
Background In a previous meta-analysis of randomized controlled trials comparing lithium
with placebo as a long-term treatment in bipolar disorders, we observed a clear preventative …

Comorbid medical illness in bipolar disorder

L Forty, A Ulanova, L Jones, I Jones… - The British Journal of …, 2014 - cambridge.org
BackgroundIndividuals with a mental health disorder appear to be at increased risk of
medical illness. AimsTo examine rates of medical illnesses in patients with bipolar disorder …

Perinatal psychiatric disorders: an overview

E Paschetta, G Berrisford, F Coccia, J Whitmore… - American journal of …, 2014 - Elsevier
Perinatal mental illness has a significant implication on maternal health, birth outcomes, and
the offspring's development. Prevalence estimates of perinatal psychiatric illnesses range …

Role of lithium augmentation in the management of major depressive disorder

M Bauer, M Adli, R Ricken, E Severus, M Pilhatsch - CNS drugs, 2014 - Springer
The high rate of non-responders to initial treatment with antidepressants requires
subsequent treatment strategies such as augmentation of antidepressants. Clinical …

A systematic review and meta-analysis of lithium augmentation of tricyclic and second generation antidepressants in major depression

JC Nelson, P Baumann, K Delucchi, R Joffe… - Journal of affective …, 2014 - Elsevier
Background Lithium augmentation of antidepressants for treatment of unipolar major
depression was one of the first adjunctive strategies based on a neuropharmacologic …

Increased psychiatric morbidity before and after the diagnosis of hypothyroidism: a nationwide register study

M Thvilum, F Brandt, D Almind, K Christensen, TH Brix… - Thyroid, 2014 - liebertpub.com
Background: Thyroid hormones are necessary for fetal brain development, and
hypothyroidism in adults has been associated with mood symptoms and reduced quality of …

Molecular actions and clinical pharmacogenetics of lithium therapy

A Can, TG Schulze, TD Gould - Pharmacology Biochemistry and Behavior, 2014 - Elsevier
Mood disorders, including bipolar disorder and depression, are relatively common human
diseases for which pharmacological treatment options are often not optimal. Among existing …

Lithium in the treatment of major depressive disorder

T Bschor - Drugs, 2014 - Springer
Recent high-quality studies have confirmed the central role of lithium in the treatment of
bipolar disorder and have established lithium as the drug of first choice for long-term …