Making room for oxytocin in understanding depression

RJ McQuaid, OA McInnis, A Abizaid… - … & Biobehavioral Reviews, 2014 - Elsevier
Depression is accompanied by an array of neurobiological variations, including altered HPA
axis activity, monoamine, growth factor and inflammatory immune functioning. In addition, a …

Oxytocin and postpartum depression: delivering on what's known and what's not

S Kim, TA Soeken, SJ Cromer, SR Martinez, LR Hardy… - Brain research, 2014 - Elsevier
The role of oxytocin in the treatment of postpartum depression has been a topic of growing
interest. This subject carries important implications, given that postpartum depression can …

Oxytocin-augmented social cognitive skills training in schizophrenia

MC Davis, MF Green, J Lee, WP Horan… - …, 2014 - nature.com
Impairments in social cognition are common in schizophrenia and predict poor functional
outcome. The purpose of this proof-of-concept randomized, parallel group clinical trial was …

Oxytocin administration enhances controlled social cognition in patients with schizophrenia

JD Woolley, B Chuang, O Lam, W Lai… - …, 2014 - Elsevier
Background Individuals with schizophrenia have functionally significant deficits in automatic
and controlled social cognition, but no currently available pharmacologic treatments reduce …

A pilot six-week randomized controlled trial of oxytocin on social cognition and social skills in schizophrenia

CM Gibson, DL Penn, KL Smedley, J Leserman… - Schizophrenia …, 2014 - Elsevier
The current study explored whether oxytocin can improve social cognition and social skills in
individuals with schizophrenia using a six-week, double-blind design. Fourteen participants …

Reduced levels of vasopressin and reduced behavioral modulation of oxytocin in psychotic disorders

LH Rubin, CS Carter, JR Bishop… - Schizophrenia …, 2014 - academic.oup.com
Oxytocin (OT) and arginine vasopressin (AVP) exert robust influence on social affiliation and
specific cognitive processes in healthy individuals. Abnormalities in these neuroendocrine …

Oxytocin enhances attention to the eye region in rhesus monkeys

O Dal Monte, PL Noble, VD Costa… - Frontiers in …, 2014 - frontiersin.org
Human and non-human primates rely on the ability to perceive and interpret facial
expressions to guide effective social interactions. The neuropeptide oxytocin (OT) has been …

Oxytocin does not improve performance of patients with schizophrenia and healthy volunteers in a facial emotion matching task

LRH de Macedo, AW Zuardi, JP Machado-de-Sousa… - Psychiatry …, 2014 - Elsevier
The neuropeptide oxytocin improves the performance in facial emotion recognition tests in
healthy volunteers and in individuals with schizophrenia. Different paradigms are used in …

The role of oxytocin in empathy to the pain of conflictual out-group members among patients with schizophrenia

A Abu-Akel, M Fischer-Shofty, Y Levkovitz… - Psychological …, 2014 - cambridge.org
Background. Oxytocin (OT) is associated with our ability to empathize and has been shown
to play a major role in mediating social behaviors within the context of intergroup dynamics …

Genes showing altered expression in the medial preoptic area in the highly social maternal phenotype are related to autism and other disorders with social deficits

TM Driessen, BE Eisinger, C Zhao, SA Stevenson… - BMC neuroscience, 2014 - Springer
Background The mother-child relationship is the most fundamental social bond in mammals,
and previous studies indicate that the medial preoptic area (MPOA) contributes to this …