Utility of transcranial ultrasound in predicting Alzheimer's disease risk

A Tomek, B Urbanová, J Hort - Journal of Alzheimer's Disease, 2014 - content.iospress.com
Alzheimer's disease (AD) is a progressive, neurodegenerative disease characterized by an
increasing incidence. One of the pathologic processes that underlie this disorder is …

Should patients with asymptomatic significant carotid stenosis undergo simultaneous carotid and cardiac surgery?

P Ogutu, R Werner, F Oertel… - … and thoracic surgery, 2014 - academic.oup.com
A best evidence topic in cardiovascular surgery was written according to a structured
protocol. The question addressed was whether patients with severe asymptomatic carotid …

Cognitive deterioration in bilateral asymptomatic severe carotid stenosis

L Buratti, C Balucani, G Viticchi, L Falsetti, C Altamura… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—This study aimed to monitor cognitive performance during a 3-
year period in subjects with bilateral asymptomatic severe internal carotid artery stenosis …

Randomized Evaluation of Carotid Occlusion and Neurocognition (RECON) trial: main results

RS Marshall, JR Festa, YK Cheung, MA Pavol… - Neurology, 2014 - AAN Enterprises
Objective: To determine whether extracranial-intracranial (EC-IC) bypass can improve
cognition over 2 years compared to best medical therapy alone in patients with symptomatic …

Investigating the non-linearity of the BOLD cerebrovascular reactivity response to targeted hypo/hypercapnia at 7 T

AA Bhogal, JCW Siero, JA Fisher, M Froeling, P Luijten… - Neuroimage, 2014 - Elsevier
Cerebrovascular reactivity (CVR) is a mechanism responsible for maintaining stable
perfusion pressure within the brain via smooth muscle mediated modulations of vascular …

Vascular impairment in Alzheimer's disease: the role of obstructive sleep apnea

L Buratti, G Viticchi, L Falsetti… - Journal of …, 2014 - content.iospress.com
Epidemiological studies have suggested a pathophysiological link between obstructive
sleep apnea syndrome (OSAS) and Alzheimer's disease (AD). The mechanism by which …

Factors affecting the determination of cerebrovascular reactivity

RE Regan, JA Fisher, J Duffin - Brain and behavior, 2014 - Wiley Online Library
Abstract Background and Purpose Cerebrovascular reactivity (CVR), measures the ability of
the cerebrovasculature to respond to vasoactive stimuli such as CO 2. CVR is often …

Reduced contralateral cerebrovascular reserve in patients with unilateral steno-occlusive disease

K Sam, E Small, J Poublanc, JS Han… - Cerebrovascular …, 2014 - karger.com
The purpose of this study was to evaluate cerebrovascular reactivity (CVR) of major arterial
vascular territories, particularly in the contralateral hemodynamically unaffected hemisphere …

Apolipoprotein E genotype and cerebrovascular alterations can influence conversion to dementia in patients with mild cognitive impairment

G Viticchi, L Falsetti, F Vernieri… - Journal of …, 2014 - content.iospress.com
The presence of apolipoprotein E (APOE) ε4 allele is the only recognized genetic risk factor
for the sporadic form of Alzheimer's disease. The aim of this study was to investigate the …

The role of neurosonology in the diagnosis of vascular dementia

G Tsivgoulis, AH Katsanos… - Journal of …, 2014 - content.iospress.com
Although transcranial sonography is not yet an established diagnostic modality for dementia
screening or differential diagnosis of Alzheimer's disease (AD) from vascular dementia …