The immune system in the female reproductive tract (FRT) does not mount an attack against
human immunodeficiency virus (HIV) or other sexually transmitted infections (STI) with a …

With aging, a general decline in immune function is observed leading to immune-
senescence. Several of these changes are gender specific affecting postmenopausal …

Embryo implantation is regulated by an inflammatory process in response to sequential
exposure to estrogen and progesterone, followed by resolution and repair. The actions of …

Embryo implantation is a crucial step for successful pregnancy. Prior to implantation, the
luminal epithelium undergoes steroid hormone-induced structural and functional changes …

Implantation is an essential process during establishment of pregnancy in mammals. It is
initiated with the attachment of the blastocyst to a receptive uterine epithelium followed by its …

Coordinated uterine-embryonic axis formation and decidual remodeling are hallmarks of
mammalian post-implantation embryo development. Embryonic-uterine orientation is …

The female reproductive tract organs of mammals, including the oviducts, uterus, cervix and
upper vagina, are derived from the Müllerian ducts, a pair of epithelial tubes that form within …

Endometriosis is a complex and enigmatic disease that arises from the interplay among
multiple genetic and environmental factors. The defining feature of endometriosis is the …

Abstract Background 70–80% of sporadic endometrial carcinomas are defined as
endometrioid carcinoma (EC). Early-stage, well differentiated endometrial carcinomas …

Sex steroids are central to sexual development and reproduction, exerting pleiotropic effects
on multiple tissues and organs throughout the lifespan of humans. Sex steroids are …