Immune regulation during chronic visceral leishmaniasis

RJ Faleiro, R Kumar, LM Hafner… - PLoS neglected tropical …, 2014 - journals.plos.org
Visceral leishmaniasis is a chronic parasitic disease associated with severe immune
dysfunction. Treatment options are limited to relatively toxic drugs, and there is no vaccine …

[HTML][HTML] Post kala-azar dermal leishmaniasis: an unresolved mystery

D Mukhopadhyay, JE Dalton, PM Kaye… - Trends in …, 2014 - cell.com
Post kala-azar dermal leishmaniasis (PKDL), a cutaneous sequela of visceral leishmaniasis
(VL), develops in some patients alongside but more commonly after apparent cure from VL …

Asymptomatic Leishmania Infection: A New Challenge for Leishmania Control

OP Singh, E Hasker, D Sacks… - Clinical Infectious …, 2014 - academic.oup.com
Asymptomatic Leishmania Infection: A New Challenge for Leishmania Control | Clinical
Infectious Diseases | Oxford Academic Skip to Main Content Advertisement Oxford Academic …

Host genetic factors in American cutaneous leishmaniasis: a critical appraisal of studies conducted in an endemic area of Brazil

LC Castellucci, LF Almeida, SE Jamieson… - Memorias do Instituto …, 2014 - SciELO Brasil
American cutaneous leishmaniasis (ACL) is a vector-transmitted infectious disease with an
estimated 1.5 million new cases per year. In Brazil, ACL represents a significant public …

[HTML][HTML] Host genetics and parasitic infections

VD Mangano, D Modiano - Clinical Microbiology and Infection, 2014 - Elsevier
Parasites still impose a high death and disability burden on human populations, and are
therefore likely to act as selective factors for genetic adaptations. Genetic epidemiological …

Lipoprotein lipase and PPAR alpha gene polymorphisms, increased very‐low‐density lipoprotein levels, and decreased high‐density lipoprotein levels as risk …

MDT Carvalho, DP Alonso… - Mediators of …, 2014 - Wiley Online Library
In visceral leishmaniasis (VL) endemic areas, a minority of infected individuals progress to
disease since most of them develop protective immunity. Therefore, we investigated the risk …

SLC11A1 polymorphisms and susceptibility to visceral leishmaniasis in Moroccan patients

R Ejghal, M Hida, ML Idrissi, A El Hessni, M Lemrani - Acta tropica, 2014 - Elsevier
Human visceral leishmaniasis is endemic in the Mediterranean basin. Since most infections
are sub-clinical or asymptomatic, host genetics can provide concrete evidence in …

[HTML][HTML] Leishmaniasis in Uganda: historical account and a review of the literature

J Olobo-Okao, P Sagaki - The Pan African Medical Journal, 2014 - ncbi.nlm.nih.gov
Visceral leishmaniasis (VL) or kala azar is a fatal and neglected disease caused by
protozoan parasites. It occurs worldwide including north-eastern Uganda. This review gives …

Os fatores de crescimento ea interleucina-4 convergem para ativar o fator de transcrição STAT6 ea expressão da arginase na leishmaniose visceral experimental

EJ Osorio Esparza - 2014 - arca.fiocruz.br
A expressão de arginase-1 (Arg1) está associada com a patogênese da leishmaniose
visceral (LV), embora os mecanismos que norteiam a sua regulação na doença não sejam …