Hysteresis loops are phenomena that sometimes are encountered in the analysis of
pharmacokinetic and pharmacodynamic relationships spanning from pre-clinical to clinical …

Count data, or number of events per time interval, are discrete data arising from repeated
time to event observations. Their mean count, or piecewise constant event rate, can be …

The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR)
Mycobacterium tuberculosis prompted the reintroduction of para-aminosalicylic acid (PAS) …

Population or other pharmacometric models are a useful means to describe, succinctly, the
relationships between drug administration, exposure (concentration), and downstream …

Extralabel drug use of penicillin G in food-producing animals may cause an excess of
residues in tissue which will have the potential to damage human health. Of all the …

Background Gaucher disease (GD) is a rare recessively inherited disorder caused by
deficiency of a lysosomal enzyme, glucocerebrosidase. Accumulation of glucosylceramide …

CPT: Pharmacometrics & Systems Pharmacology (PSP) was launched in September 2012
and, since then, has published at least one new article every week on average. As a result …