[PDF][PDF] Understanding the hysteresis loop conundrum in pharmacokinetic/pharmacodynamic relationships
Hysteresis loops are phenomena that sometimes are encountered in the analysis of
pharmacokinetic and pharmacodynamic relationships spanning from pre-clinical to clinical …
pharmacokinetic and pharmacodynamic relationships spanning from pre-clinical to clinical …
Modeling and simulation of count data
EL Plan - CPT: pharmacometrics & systems pharmacology, 2014 - Wiley Online Library
Count data, or number of events per time interval, are discrete data arising from repeated
time to event observations. Their mean count, or piecewise constant event rate, can be …
time to event observations. Their mean count, or piecewise constant event rate, can be …
Pharmacokinetics of para-Aminosalicylic Acid in HIV-Uninfected and HIV-Coinfected Tuberculosis Patients Receiving Antiretroviral Therapy, Managed for Multidrug …
L de Kock, SKB Sy, B Rosenkranz… - Antimicrobial agents …, 2014 - Am Soc Microbiol
The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR)
Mycobacterium tuberculosis prompted the reintroduction of para-aminosalicylic acid (PAS) …
Mycobacterium tuberculosis prompted the reintroduction of para-aminosalicylic acid (PAS) …
Visualization and communication of pharmacometric models with Berkeley Madonna
Population or other pharmacometric models are a useful means to describe, succinctly, the
relationships between drug administration, exposure (concentration), and downstream …
relationships between drug administration, exposure (concentration), and downstream …
Interspecies mixed-effect pharmacokinetic modeling of penicillin G in cattle and swine
Extralabel drug use of penicillin G in food-producing animals may cause an excess of
residues in tissue which will have the potential to damage human health. Of all the …
residues in tissue which will have the potential to damage human health. Of all the …
Modeling changes in biomarkers in Gaucher disease patients receiving enzyme replacement therapy using a pathophysiological model
M Vigan, J Stirnemann, C Caillaud, R Froissart… - Orphanet journal of rare …, 2014 - Springer
Background Gaucher disease (GD) is a rare recessively inherited disorder caused by
deficiency of a lysosomal enzyme, glucocerebrosidase. Accumulation of glucosylceramide …
deficiency of a lysosomal enzyme, glucocerebrosidase. Accumulation of glucosylceramide …
[HTML][HTML] CPT: Pharmacometrics & Systems Pharmacology Publishes Its 100th Article
PH van der Graaf, LE Friberg - CPT: Pharmacometrics & Systems …, 2014 - ncbi.nlm.nih.gov
CPT: Pharmacometrics & Systems Pharmacology (PSP) was launched in September 2012
and, since then, has published at least one new article every week on average. As a result …
and, since then, has published at least one new article every week on average. As a result …