Type VI secretion system effectors: poisons with a purpose

AB Russell, SB Peterson, JD Mougous - Nature reviews microbiology, 2014 - nature.com
The type VI secretion system (T6SS) mediates interactions between a broad range of Gram-
negative bacterial species. Recent studies have led to a substantial increase in the number …

Antibiotic resistance in Pseudomonas aeruginosa biofilms: towards the development of novel anti-biofilm therapies

PK Taylor, ATY Yeung, REW Hancock - Journal of biotechnology, 2014 - Elsevier
The growth of bacteria as structured aggregates termed biofilms leads to their protection
from harsh environmental conditions such as physical and chemical stresses, shearing …

[HTML][HTML] Pseudomonas aeruginosa Diversification during Infection Development in Cystic Fibrosis Lungs—A Review

AM Sousa, MO Pereira - Pathogens, 2014 - mdpi.com
Pseudomonas aeruginosa is the most prevalent pathogen of cystic fibrosis (CF) lung
disease. Its long persistence in CF airways is associated with sophisticated mechanisms of …

Cystic Fibrosis Foundation Pulmonary Guideline. Pharmacologic Approaches to Prevention and Eradication of Initial Pseudomonas aeruginosa Infection

PJ Mogayzel Jr, ET Naureckas… - Annals of the …, 2014 - atsjournals.org
Description: The Cystic Fibrosis (CF) Foundation developed clinical care guidelines for the
prevention of Pseudomonas aeruginosa infection, the treatment of initial P. aeruginosa …

Microbial biofilm formation: a need to act.

U Römling, S Kjelleberg, S Normark… - Journal of internal …, 2014 - search.ebscohost.com
The article discusses the history of microbial biofilm information and its essence to
healthcare, as addressed at the 60th Nobel Conference on Biofilm Formation held in Solna …

Siderophore-dependent iron uptake systems as gates for antibiotic Trojan horse strategies against Pseudomonas aeruginosa

GLA Mislin, IJ Schalk - Metallomics, 2014 - academic.oup.com
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen responsible for
nosocomial infections. The prevalence of antibiotic-resistant P. aeruginosa strains is …

[HTML][HTML] Adaptation of Pseudomonas aeruginosa in Cystic Fibrosis Airways Influences Virulence of Staphylococcus aureus In Vitro and Murine Models of Co …

R Baldan, C Cigana, F Testa, I Bianconi, M De Simone… - PloS one, 2014 - journals.plos.org
Cystic fibrosis (CF) airways disease represents an example of polymicrobial infection
whereby different bacterial species can interact and influence each other. In CF patients …

Mechanisms of phagocytosis and host clearance of Pseudomonas aeruginosa

RR Lovewell, YR Patankar… - American Journal of …, 2014 - journals.physiology.org
Pseudomonas aeruginosa is an opportunistic bacterial pathogen responsible for a high
incidence of acute and chronic pulmonary infection. These infections are particularly …

[HTML][HTML] Regulation of Hfq by the RNA CrcZ in Pseudomonas aeruginosa Carbon Catabolite Repression

E Sonnleitner, U Bläsi - PLoS Genetics, 2014 - journals.plos.org
Carbon Catabolite repression (CCR) allows a fast adaptation of Bacteria to changing
nutrient supplies. The Pseudomonas aeruginosa (PAO1) catabolite repression control …

Vaccines for Pseudomonas aeruginosa: a long and winding road

GP Priebe, JB Goldberg - Expert review of vaccines, 2014 - Taylor & Francis
Despite the recognition of Pseudomonas aeruginosa as an opportunistic pathogen, no
vaccine against this bacteria has come to market. This review describes the current state-of …