[HTML][HTML] Inflammation early in life is a vulnerability factor for emotional behavior at adolescence and for lipopolysaccharide-induced spatial memory and neurogenesis …

AL Dinel, C Joffre, P Trifilieff, A Aubert, A Foury… - Journal of …, 2014 - Springer
Background The postnatal period is a critical time window during which inflammatory events
have significant and enduring effects on the brain, and as a consequence, induce alterations …

Serotonergic pharmacology in animal models: From behavioral disorders to dyskinesia

M Beaudoin-Gobert, V Sgambato-Faure - Neuropharmacology, 2014 - Elsevier
Abstract Serotonin (5-HT) dysfunction has been involved in both movement and behavioral
disorders. Serotonin pharmacology improves dyskinetic movements as well as depressive …

A randomised, double‐blind, placebo‐controlled, duloxetine‐referenced study of the efficacy and tolerability of vortioxetine in the acute treatment of adults with …

AR Mahableshwarkar, PL Jacobsen… - … journal of clinical …, 2014 - Wiley Online Library
Aims This study aims to evaluate the efficacy and tolerability of vortioxetine 2.5‐, 5‐and 10‐
mg once‐daily doses vs. placebo in the treatment of generalised anxiety disorder (GAD) …

Rivastigmine improves hippocampal neurogenesis and depression-like behaviors via 5-HT1A receptor stimulation in olfactory bulbectomized mice

MR Islam, S Moriguchi, H Tagashira, K Fukunaga - Neuroscience, 2014 - Elsevier
Rivastigmine is a non-competitive inhibitor of both acetylcholinesterase (AChE) and
butylcholinesterase (BuChE) used to treat mild to moderate dementia in Alzheimer's disease …

Antidepressant effects on serotonin 1A/1B receptors in the rat brain using a gene x environment model

SS Shrestha, DS Pine, DA Luckenbaugh, K Varnäs… - Neuroscience …, 2014 - Elsevier
A gene-environment (GxE) interaction is implicated in both the pathophysiology and
treatment of major depressive disorder (MDD). This study modeled the effects of genetic …

桑叶抗焦虑作用研究

罗旭梅, 夏爽, 刘汉儒, 高倩, 陈超, 李学刚 - 中兽医医药杂志, 2014 - cqvip.com
目的: 利用焦虑动物模型研究桑叶抗焦虑作用及其物质基础. 方法: 将小鼠随机分为空白对照组(
蒸馏水0.375 mL), 地西泮对照组(0.0023 g/kg), 桑叶组(4.5 g/kg), 真空处理桑叶组(4.5 g/kg) …

5-HT1B autoreceptors: molecular mechanisms and behavioral implications

Y Liu - 2014 - digital.lib.washington.edu
The serotonergic system is important in modulating a range of emotional behaviors, and
disturbances of this system are implicated in psychiatric conditions such as post-traumatic …

[PDF][PDF] ВЛИЯНИЕ ПСИХОТРОПНОГО ПРЕПАРАТА TC-2153 НА ПОВЕДЕНИЕ И ЭКСПРЕССИЮ ГЕНОВ СЕРОТОНИНОВОЙ СИСТЕМЫ И …

ЕА Куликова - neuronm.ru
Депрессия-это тяжелое психическое заболевание. Известно, что 26% женщин и 12%
мужчин в развитых странах страдают депрессией. По данным Всемирной Организации …

BRAIN MICRODIALYSIS IN KNOCKOUT MICE: DRAWBACKS AND ADVANTAGES TO STUDY THE ROLE OF 5-HT1A AND 5-HT1B AUTORECEPTORS IN THE …

AM GARDIER - Neurobiology of Mood Disorders, 2014 - books.google.com
From anesthetized rats in the 90s to conscious wild-type or knockout mice today,
intracerebral in vivo microdialysis provided important information about the brain …