The importance of chronic low-grade inflammation in the pathology of numerous age-related
chronic conditions is now clear. An unresolved inflammatory response is likely to be …

IL-1β production is critically regulated by cytosolic molecular complexes, termed
inflammasomes. Different inflammasome complexes have been described to date. While all …

Abstract An Expert Panel convened by the National Lipid Association previously developed
a consensus set of recommendations for the patient-centered management of dyslipidemia …

Macrophage accumulation within the vascular wall is a hallmark of atherosclerosis. In
atherosclerotic lesions, macrophages respond to various environmental stimuli, such as …

Sleep has a critical role in promoting health. Research over the past decade has
documented that sleep disturbance has a powerful influence on the risk of infectious …

Arterial stiffening occurs with age and is closely associated with the progression of
cardiovascular disease. Stiffening is most often studied at the level of the whole vessel …

Acute inflammatory responses are protective, yet without timely resolution can lead to
chronic inflammation and organ fibrosis. A systems approach to investigate self-limited (self …

Atherosclerosis is a chronic progressive vascular disease. It starts early in life, has a long
asymptomatic phase, and a progression accelerated by various cardiovascular risk factors …

Patients with rheumatoid arthritis (RA) and other inflammatory joint diseases (IJDs) have an
increased risk of premature death compared with the general population, mainly because of …

Atherosclerosis is a chronic inflammatory disease associated with cardiovascular
dysfunction including myocardial infarction, unstable angina, sudden cardiac death, stroke …