Nanomaterials promise to improve disease diagnosis and treatment by enhancing the
delivery of drugs, genes, biomolecules and imaging agents to specific subcellular targets. In …

Acute and chronic pain control is a significant clinical challenge that has been largely unmet.
Local anesthetics are widely used for the control of post-operative pain and in the therapy of …

A pH-responsive light-up nanoparticle probe with aggregation-induced emission (AIE)
features was designed and synthesized. The probe carries negative charges and shows …

We designed a study for photodynamic therapy (PDT) using chitosan coated Mg–Al layered
double hydroxide (LDH) nanoparticles as the delivery system. A Food and Drug …

Poor solubility of active pharmaceutical ingredients (APIs) is a great challenge for the
pharmaceutical industry and, hence, drug nanocrystals are widely studied as one solution to …

Tetraphenylethene (TPE) derivatives characterized with distinct aggregation-induced-
emission, attempted to aggregate with doxorubicin (Dox) to formulate the interior …

A new kind of pH and temperature responsive poly (acrylamide‐co‐itaconic acid) hydrogel
was prepared by free radical polymerization using ammonium persulfate as initiator and …

Drug delivery systems could potentially overcome low bioavailability and gastrointestinal
toxicity, which are the major challenges for the development of oral anticancer drugs …

In the present study, we constructed a tumor-targeting and pH-sensitive lipoprotein-mimic
nanocarrier containing paclitaxel (FA-BSA-LC/DOPE-PTX), by adding 1, 2-dioleoyl-sn …

In a preceding study we have recently established an in vivo visualization system for the
geranylgeranylation of proteins in a stably transformed tobacco BY-2 cell line, which …