High specific selectivity and membrane-active mechanism of the synthetic centrosymmetric α-helical peptides with Gly-Gly pairs

J Wang, S Chou, L Xu, X Zhu, N Dong, A Shan… - Scientific reports, 2015 - nature.com
We used a template-assisted approach to develop synthetic antimicrobial peptides, which
differ from naturally occurring antimicrobial peptides that can compromise host natural …

Conjugation of aurein 2.2 to HPG yields an antimicrobial with better properties

P Kumar, RA Shenoi, BFL Lai, M Nguyen… - …, 2015 - ACS Publications
Aurein 2.2 is an antimicrobial peptide (AMP) whose mechanism of action is quite well-
understood and that has good activity against Gram-positive bacteria. It is, however, highly …

[PDF][PDF] Antimicrobial and antioxidative activities of peptides from goat milk hydrolyzed with various protease.

E Kusumaningtyas, R Widiastuti, HD Kusumaningrum… - 2015 - medpub.appertani.org
Milk is highly nutritious food containing protein as a good source of bioactive peptide that
beneficial for health. This research was aimed to explore potency of bioactive peptide …

Insights into the packing switching of the EphA2 transmembrane domain by molecular dynamic simulations

F Sun, L Xu, P Chen, P Wei, J Qu… - The Journal of …, 2015 - ACS Publications
Receptor tyrosine kinases play an important role in mediating cell migration and adhesion
associated with various biology processes. With a single-span transmembrane domain …

Investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical Staphylococcus aureus infections

JT Ravensdale - 2015 - espace.curtin.edu.au
In this study, resistance towards antimicrobial peptides developed rapidly in MRSA, but
resistance was mitigated by controlling the environment in which the cells are treated …