An insight into cochleates, a potential drug delivery system
Cochleates, a type of lipid based drug delivery system, are solid particulates made up of
large continuous lipid bilayer sheets rolled up in a spiral structure with little or no internal …
large continuous lipid bilayer sheets rolled up in a spiral structure with little or no internal …
Improved stability and skin permeability of sodium hyaluronate-chitosan multilayered liposomes by Layer-by-Layer electrostatic deposition for quercetin delivery
S Jeon, CY Yoo, SN Park - Colloids and surfaces B: biointerfaces, 2015 - Elsevier
Abstract Layer-by-Layer (LbL) technology, based on the electrostatic interaction of
polyelectrolytes, is used to improve the stability of drug delivery systems. In the present …
polyelectrolytes, is used to improve the stability of drug delivery systems. In the present …
Investigating the role of Pluronic-g-Cationic polyelectrolyte as functional stabilizer for nanocrystals: Impact on Paclitaxel oral bioavailability and tumor growth
Paclitaxel (PTX) is a potent anticancer drug which suffers limitations of extremely low oral
bioavailability due to low solubility, rapid metabolism and efflux by P-gp transporters. The …
bioavailability due to low solubility, rapid metabolism and efflux by P-gp transporters. The …
TPGS-chitosome as an effective oral delivery system for improving the bioavailability of Coenzyme Q10
Y Shao, L Yang, HK Han - European journal of pharmaceutics and …, 2015 - Elsevier
This study aimed to design the chitosan coated TPGS liposome to enhance the
bioavailability of Coenzyme Q10 (CoQ10). Optimization of formulation variables for the …
bioavailability of Coenzyme Q10 (CoQ10). Optimization of formulation variables for the …
Formulation and in vitro evaluation of berberine containing liposome optimized by 32 full factorial designs
The present study demonstrates the application of 32 full factorial design for optimization of
berberine loaded liposome for oral administration. Thin film hydration method was used to …
berberine loaded liposome for oral administration. Thin film hydration method was used to …
In Vivo Evaluation of Paclitaxel-Loaded Lipid Nanocapsules After Intravenous and Oral Administration on Resistant Tumor
AC Groo, M Bossiere, L Trichard, P Legras… - …, 2015 - Taylor & Francis
Aim & methods: The aim of the present work was to encapsulate paclitaxel (Ptx) in various
lipid nanocapsules (LNCs) formulations and then to compare their pharmacokinetics and …
lipid nanocapsules (LNCs) formulations and then to compare their pharmacokinetics and …
Improved oral bioavailability of docetaxel by nanostructured lipid carriers: in vitro characteristics, in vivo evaluation and intestinal transport studies
G Fang, B Tang, Y Chao, Y Zhang, H Xu, X Tang - RSC advances, 2015 - pubs.rsc.org
The objective of the current study was to explore the potential of nanostructured lipid carriers
(NLC) for oral delivery of docetaxel (DTX) and investigate the absorption mechanism in vivo …
(NLC) for oral delivery of docetaxel (DTX) and investigate the absorption mechanism in vivo …
Inhibition of aggregation of mutant huntingtin by nucleic acid aptamers in vitro and in a yeast model of Huntington's disease
Elongated polyglutamine stretch in mutant huntingtin (mhtt) correlates well with the
pathology of Huntington's disease (HD). Inhibition of aggregation of mhtt is a promising …
pathology of Huntington's disease (HD). Inhibition of aggregation of mhtt is a promising …
Recent advances in tumor targeting approaches
Tremendous technological advancement has been observed in the past few decades to
combat ever increasing mortality rate in cancer therapy. It is now widely accepted that this …
combat ever increasing mortality rate in cancer therapy. It is now widely accepted that this …
Cyclosporine A loaded self-nanoemulsifying drug delivery system (SNEDDS): implication of a functional excipient based co-encapsulation strategy on oral …
The present work focusses on the formulation development and evaluation of a functional
excipient (surfactant stabilizer), a vitamin E TPGS loaded self-nanoemulsifying drug delivery …
excipient (surfactant stabilizer), a vitamin E TPGS loaded self-nanoemulsifying drug delivery …