Random monoallelic expression (RME) of genes represents a striking example of how
stochastic molecular processes can result in cellular heterogeneity. Recent transcriptome …

The sense of smell collects vital information about the environment by detecting a multitude
of chemical odorants. Breadth and sensitivity are provided by a huge number of …

Migratory species depend on a suite of interconnected sites. Threats to unprotected links in
these chains of sites are driving rapid population declines of migrants around the world, yet …

Animals have evolved homeostatic responses to changes in oxygen availability that act on
different timescales. Although the hypoxia-inducible factor (HIF) transcriptional pathway that …

The sense of smell allows chemicals to be perceived as diverse scents. We used single-
neuron RNA sequencing to explore the developmental mechanisms that shape this ability …

The mouse olfactory mucosa is a complex chemosensory tissue composed of multiple cell
types, neuronal and non-neuronal. We have here applied RNA-seq hierarchically, in three …

The study of gene expression in mammalian single cells via genomic technologies now
provides the possibility to investigate the patterns of allelic gene expression. We used single …

The mammalian olfactory system uses a large family of odorant receptors (ORs) to detect
and discriminate amongst a myriad of volatile odor molecules. Understanding odor coding …

Olfactory receptor (OR)-associated events are mediated by well-conserved components in
the olfactory epithelium, including olfactory G-protein (Golf), adenylate cyclase III (ACIII), and …

This review reports on the knowledge about odourant–olfactory receptor interactions and
their projection within the field of structure–odour relationships (SOR). We provide a list of …