Evidence for archaic adaptive introgression in humans

F Racimo, S Sankararaman, R Nielsen… - Nature Reviews …, 2015 - nature.com
As modern and ancient DNA sequence data from diverse human populations accumulate,
evidence is increasing in support of the existence of beneficial variants acquired from …

[HTML][HTML] Mitochondrial DNA variation in human radiation and disease

DC Wallace - Cell, 2015 - cell.com
Environmental adaptation, predisposition to common diseases, and, potentially, speciation
may all be linked through the adaptive potential of mitochondrial DNA (mtDNA) alterations of …

Detecting balancing selection in genomes: limits and prospects

A Fijarczyk, W Babik - Molecular ecology, 2015 - Wiley Online Library
In spite of the long‐term interest in the process of balancing selection, its frequency in
genomes and evolutionary significance remain unclear due to challenges related to its …

Population genetic differentiation of height and body mass index across Europe

MR Robinson, G Hemani, C Medina-Gomez… - Nature …, 2015 - nature.com
Across-nation differences in the mean values for complex traits are common,,,,,,,, but the
reasons for these differences are unknown. Here we find that many independent loci …

Matriglycan: a novel polysaccharide that links dystroglycan to the basement membrane

T Yoshida-Moriguchi, KP Campbell - Glycobiology, 2015 - academic.oup.com
Associations between cells and the basement membrane are critical for a variety of
biological events including cell proliferation, cell migration, cell differentiation and the …

[HTML][HTML] Zebrafish stripes as a model for vertebrate colour pattern formation

AP Singh, C Nüsslein-Volhard - Current Biology, 2015 - cell.com
Colour patterns are prominent features of many animals and have important functions in
communication, such as camouflage, kin recognition and mate choice. As targets for natural …

Genomic analyses reveal potential independent adaptation to high altitude in Tibetan chickens

MS Wang, Y Li, MS Peng, LI Zhong… - Molecular biology …, 2015 - academic.oup.com
Much like other indigenous domesticated animals, Tibetan chickens living at high altitudes
(2,200–4,100 m) show specific physiological adaptations to the extreme environmental …

[HTML][HTML] Detection of selection signatures in dairy and beef cattle using high-density genomic information

F Zhao, S McParland, F Kearney, L Du… - Genetics Selection …, 2015 - Springer
Background Artificial selection for economically important traits in cattle is expected to have
left distinctive selection signatures on the genome. Access to high-density genotypes …

[HTML][HTML] Genetics of autoimmune diseases: insights from population genetics

PS Ramos, AM Shedlock, CD Langefeld - Journal of human genetics, 2015 - nature.com
Human genetic diversity is the result of population genetic forces. This genetic variation
influences disease risk and contributes to health disparities. Autoimmune diseases (ADs) …

Altitude adaptation: a glimpse through various lenses

TS Simonson - High altitude medicine & biology, 2015 - liebertpub.com
Abstract Simonson, Tatum S. Altitude adaptation: A glimpse through various lenses. High Alt
Med Biol 16: 125–137, 2015.—Recent availability of genome-wide data from highland …