Evidence for archaic adaptive introgression in humans
As modern and ancient DNA sequence data from diverse human populations accumulate,
evidence is increasing in support of the existence of beneficial variants acquired from …
evidence is increasing in support of the existence of beneficial variants acquired from …
[HTML][HTML] Mitochondrial DNA variation in human radiation and disease
DC Wallace - Cell, 2015 - cell.com
Environmental adaptation, predisposition to common diseases, and, potentially, speciation
may all be linked through the adaptive potential of mitochondrial DNA (mtDNA) alterations of …
may all be linked through the adaptive potential of mitochondrial DNA (mtDNA) alterations of …
Detecting balancing selection in genomes: limits and prospects
A Fijarczyk, W Babik - Molecular ecology, 2015 - Wiley Online Library
In spite of the long‐term interest in the process of balancing selection, its frequency in
genomes and evolutionary significance remain unclear due to challenges related to its …
genomes and evolutionary significance remain unclear due to challenges related to its …
Population genetic differentiation of height and body mass index across Europe
MR Robinson, G Hemani, C Medina-Gomez… - Nature …, 2015 - nature.com
Across-nation differences in the mean values for complex traits are common,,,,,,,, but the
reasons for these differences are unknown. Here we find that many independent loci …
reasons for these differences are unknown. Here we find that many independent loci …
Matriglycan: a novel polysaccharide that links dystroglycan to the basement membrane
T Yoshida-Moriguchi, KP Campbell - Glycobiology, 2015 - academic.oup.com
Associations between cells and the basement membrane are critical for a variety of
biological events including cell proliferation, cell migration, cell differentiation and the …
biological events including cell proliferation, cell migration, cell differentiation and the …
[HTML][HTML] Zebrafish stripes as a model for vertebrate colour pattern formation
AP Singh, C Nüsslein-Volhard - Current Biology, 2015 - cell.com
Colour patterns are prominent features of many animals and have important functions in
communication, such as camouflage, kin recognition and mate choice. As targets for natural …
communication, such as camouflage, kin recognition and mate choice. As targets for natural …
Genomic analyses reveal potential independent adaptation to high altitude in Tibetan chickens
MS Wang, Y Li, MS Peng, LI Zhong… - Molecular biology …, 2015 - academic.oup.com
Much like other indigenous domesticated animals, Tibetan chickens living at high altitudes
(2,200–4,100 m) show specific physiological adaptations to the extreme environmental …
(2,200–4,100 m) show specific physiological adaptations to the extreme environmental …
[HTML][HTML] Detection of selection signatures in dairy and beef cattle using high-density genomic information
F Zhao, S McParland, F Kearney, L Du… - Genetics Selection …, 2015 - Springer
Background Artificial selection for economically important traits in cattle is expected to have
left distinctive selection signatures on the genome. Access to high-density genotypes …
left distinctive selection signatures on the genome. Access to high-density genotypes …
[HTML][HTML] Genetics of autoimmune diseases: insights from population genetics
PS Ramos, AM Shedlock, CD Langefeld - Journal of human genetics, 2015 - nature.com
Human genetic diversity is the result of population genetic forces. This genetic variation
influences disease risk and contributes to health disparities. Autoimmune diseases (ADs) …
influences disease risk and contributes to health disparities. Autoimmune diseases (ADs) …
Altitude adaptation: a glimpse through various lenses
TS Simonson - High altitude medicine & biology, 2015 - liebertpub.com
Abstract Simonson, Tatum S. Altitude adaptation: A glimpse through various lenses. High Alt
Med Biol 16: 125–137, 2015.—Recent availability of genome-wide data from highland …
Med Biol 16: 125–137, 2015.—Recent availability of genome-wide data from highland …