The co-occurrence of both Alzheimer disease (AD) pathology and vascular brain injury (VBI)
is very common, especially amongst the oldest of old. In neuropathologic studies, the …

However, an unresolved issue remains on the temporal relationship between the
development of vascular and amyloid pathologies as other potential factors, such as the …

Introduction The aim of this study was to test the diagnostic value of cerebrospinal fluid
(CSF) beta-amyloid (Aβ 1–42), phosphorylated tau, and total tau (tau) to discriminate …

Background: We tested our hypothesis that the white matter network might mediate the effect
of amyloid and small vessel disease (SVD) on cortical thickness and/or cognition. Methods …

Cognitive reserve is the ability to sustain cognitive function even with a certain amount of
brain damages. Here we investigate the neural compensation mechanism of cognitive …

Objective: To determine the independent and synergistic effects of amyloid and small vessel
disease (SVD) burden on longitudinal cognitive decline in patients with subcortical vascular …

The purposes of the present study were to explore whether hippocampal atrophy exists in
pure subcortical vascular dementia (SVaD) as defined by negative 11 C-Pittsburg …

Objective: To investigate the prevalence and associations of cortical superficial siderosis
(cSS) utilizing MRI markers of cerebral small vessel disease and amyloid burden assessed …

Aims Neuroimaging studies have demonstrated both structural and functional abnormalities
in widespread brain regions in patients with subcortical vascular mild cognitive impairment …

Objective To evaluate neurophysiological features of M1 excitability and plasticity in
Subcortical Ischemic Vascular Dementia (SIVD), by means of a TMS mapping study …