The echinocandins are large lipopeptide molecules that, since their discovery approximately
41 years ago, have emerged as important additions to the expanding armamentarium …

Invasive aspergillosis remains an often fatal, difficult-to treat infection in
immunocompromised patients. Patients not classically defined as immunocompromised …

This article has been corrected. The original version (PDF) is appended to this article as a
Supplement. Background: Invasive aspergillosis (IA) is associated with poor outcomes in …

Invasive aspergillosis (IA) is a life-threatening infection in severely immunocompromised
haematological malignancy patients. In this study, the efficacy and safety of caspofungin …

Several new antifungal agents are currently in various stages of development. This is
promising, as there is a continued need for new agents to treat invasive fungal infections …

Triazole antifungals are frontline drugs for the treatment and prophylaxis of infections due to
Aspergillus species. Azole resistance is an emerging problem and is associated with …

Invasive mould diseases (IMDs) are often encountered in haematologic patients who
undergo chemotherapy or who require allogeneic haematopoietic stem cell transplantation …

Invasive fungal infections have increase worldwide and represent a threat for
immunocompromised patients including HIV-infected, recipients of solid organ and stem cell …

The incidence of severe fungal infections has increased worldwide and represents a serious
threat, especially among immunocompromised and critically ill patients. Most common …

ABSTRACT ASP9726 is an investigational echinocandin with in vitro activity against
Aspergillus species. We evaluated the pharmacokinetics and efficacy of this agent in an …