Water-soluble ruthenium (II) complexes with chiral 4-(2, 3-dihydroxypropyl)-formamide oxoaporphine (FOA): in vitro and in vivo anticancer activity by stabilization of G …
ZF Chen, QP Qin, JL Qin, J Zhou, YL Li… - Journal of Medicinal …, 2015 - ACS Publications
Three water-soluble ruthenium (II) complexes with chiral 4-(2, 3-dihydroxypropyl)-formamide
oxoaporphine (FOA) were synthesized and characterized. It was found that these ruthenium …
oxoaporphine (FOA) were synthesized and characterized. It was found that these ruthenium …
Biologically active [Pd 2 L 4] 4+ quadruply-stranded helicates: stability and cytotoxicity
There is emerging interest in the anti-proliferative effects of metallosupramolecular systems
due to the different size and shape of these metallo-architectures compared to traditional …
due to the different size and shape of these metallo-architectures compared to traditional …
Engineering gold nanoparticles with DNA ligands for selective catalytic oxidation of chiral substrates
Noble metal nanoparticles are promising materials for heterogeneous enantioselective
catalysis because of their high surface-to-volume ratios, large concentrations of highly …
catalysis because of their high surface-to-volume ratios, large concentrations of highly …
Synthesis, structure, stability and antimicrobial activity of a ruthenium (II) helicate derived from a bis-bidentate “click” pyridyl-1, 2, 3-triazole ligand
SV Kumar, WKC Lo, HJL Brooks, JD Crowley - Inorganica Chimica Acta, 2015 - Elsevier
Abstract A [Ru 2 L 3] 4+ ruthenium (II) triply-stranded helicate was synthesized from a bis-
bidentate “click” pyridyl-1, 2, 3-triazole ligand and RuCl 3 in good yield (58%). The helicate …
bidentate “click” pyridyl-1, 2, 3-triazole ligand and RuCl 3 in good yield (58%). The helicate …
Luminescence switch-on assay of interferon-gamma using a G-quadruplex-selective iridium (III) complex
S Lin, B He, C Yang, CH Leung, JL Mergny… - Chemical …, 2015 - pubs.rsc.org
In this study, we synthesized a series of 9 luminescent iridium (III) complexes and studied
their ability to function as luminescent probes for G-quadruplex DNA. The iridium (III) …
their ability to function as luminescent probes for G-quadruplex DNA. The iridium (III) …
Binding Behaviors for Different Types of DNA G‐Quadruplexes: Enantiomers of [Ru(bpy)2(L)]2+ (L=dppz, dppz‐idzo)
S Shi, JH Xu, X Gao, HL Huang… - Chemistry–A European …, 2015 - Wiley Online Library
Polymorphic DNA G‐quadruplex recognition has attracted great interest in recent years. The
strong binding affinity and potential enantioselectivity of chiral [Ru (bpy) 2 (L)] 2+(L= dipyrido …
strong binding affinity and potential enantioselectivity of chiral [Ru (bpy) 2 (L)] 2+(L= dipyrido …
Cationic azacryptands as selective three-way DNA junction binding agents
J Novotna, A Laguerre, A Granzhan… - Organic & …, 2015 - pubs.rsc.org
DNA damaging agents are among the most powerful anticancer drugs currently in clinical
use. As an alternative to irreversible nucleobase damage and DNA strand breaks, the non …
use. As an alternative to irreversible nucleobase damage and DNA strand breaks, the non …
Selective nuclei accumulation of ruthenium (II) complex enantiomers that target G-quadruplex DNA
D Sun, Y Liu, Q Yu, D Liu, Y Zhou, J Liu - Journal of Inorganic Biochemistry, 2015 - Elsevier
Different enantiomers exhibit large differences in their biological activity and/or toxicity, but
they rarely involve the relationship of the agents for molecular and cellular imaging with the …
they rarely involve the relationship of the agents for molecular and cellular imaging with the …
Recognition of DNA/RNA bulges by antimicrobial and antitumor metallohelices
Bulged structures have been identified in nucleic acids and have been shown to be linked to
biomolecular processes involved in numerous diseases. Thus, chemical agents with affinity …
biomolecular processes involved in numerous diseases. Thus, chemical agents with affinity …
Iron (II) supramolecular helicates condense plasmid DNA and inhibit vital DNA‐related enzymatic activities
J Malina, MJ Hannon, V Brabec - Chemistry–A European …, 2015 - Wiley Online Library
The dinuclear iron (II) supramolecular helicates [Fe2L3] Cl4 (L= C25H20N4) bind to DNA
through noncovalent (ie, hydrogen‐bonding, electrostatic) interactions and exhibit …
through noncovalent (ie, hydrogen‐bonding, electrostatic) interactions and exhibit …