Obesity is a major health burden with an increased risk of cardiovascular morbidity and
mortality. Endothelial dysfunction is pivotal to the development of cardiovascular disease …

Since the discovery of leptin in 1994 by Zhang et al., there have been a number of reports
showing its implication in the development of a wide range of cardiovascular diseases …

Objectives The aim of this study was to review the effect of a low advanced glycation end
product (AGEs) diet, exercise, and a combination of both on circulating AGE levels as well …

Background: Obesity and lipid profile are major risk factors for noncommunicable diseases,
especially cardiovascular diseases and diabetes. In this regard, improving indicators of …

Mouse and human induced pluripotent stem cells (iPSCs) may represent a novel approach
for modeling diabetes. Taking this into consideration, the aim of this study was to generate …

Epidemiological evidence has shown that abdominal obesity is closely associated with the
development of cardiovascular (CV) disease, suggesting that it might be considered as an …

Objective Elevated levels of serum leptin are associated with increased adiposity and
production of pro-inflammatory cytokines. Both cytokines and body adiposity have been …

Objectives: Although metabolic syndrome is associated with increased sympathetic activity
that chronically stimulates β-adrenoceptors, the β-adrenoceptor signaling pathway has been …

The preventative effect of insulin plant (Costus pictus) leaf extract on hyperglycaemia, insulin
sensitivity and dyslipidaemia in fructose-fed insulin resistant rats was investigated in the …

Objectives Police officers have a high prevalence of cardiovascular disease (CVD).
Reduced heart rate variability (HRV) is known to increase CVD risk. Leptin and adiponectin …