[HTML][HTML] Gut chemosensing mechanisms
A Psichas, F Reimann, FM Gribble - The Journal of clinical …, 2015 - Am Soc Clin Investig
The enteroendocrine system is the primary sensor of ingested nutrients and is responsible
for secreting an array of gut hormones, which modulate multiple physiological responses …
for secreting an array of gut hormones, which modulate multiple physiological responses …
PACAP as a neuroprotective factor in ischemic neuronal injuries
S Shioda, T Nakamachi - Peptides, 2015 - Elsevier
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 27-or 38-amino acid
neuropeptide, which belongs to the vasoactive intestinal polypeptide/glucagon/secretin …
neuropeptide, which belongs to the vasoactive intestinal polypeptide/glucagon/secretin …
Regulation of appetite, body composition, and metabolic hormones by vasoactive intestinal polypeptide (VIP)
JP Vu, M Larauche, M Flores, L Luong, J Norris… - Journal of Molecular …, 2015 - Springer
Vasoactive intestinal peptide (VIP) is a 28-amino acid neuropeptide that belongs to the
secretin-glucagon superfamily of peptides and has 68% homology with PACAP. VIP is …
secretin-glucagon superfamily of peptides and has 68% homology with PACAP. VIP is …
[HTML][HTML] Isolation and characterisation of a novel trophoblast side-population from first trimester placentae
JL James, DG Hurley, T Gamage, T Zhang… - …, 2015 - rep.bioscientifica.com
The placenta is responsible for all nutrient and gas exchange between mother and baby
during pregnancy. The differentiation of specialised placental epithelial cells called …
during pregnancy. The differentiation of specialised placental epithelial cells called …
A structure–function study of PACAP using conformationally restricted analogs: Identification of PAC1 receptor-selective PACAP agonists
I Ramos-Álvarez, SA Mantey, T Nakamura… - Peptides, 2015 - Elsevier
Pituitary adenylate cyclase-activating polypeptide (PACAP) has widespread physiological/
pathophysiological actions and there is increased interest for its use therapeutically …
pathophysiological actions and there is increased interest for its use therapeutically …
PACAP modulates the consolidation and extinction of the contextual fear conditioning through NMDA receptors
SD Schmidt, JC Myskiw, CRG Furini, BE Schmidt… - Neurobiology of learning …, 2015 - Elsevier
Pituitary adenylate cyclase-activating polypeptide (PACAP) has a broad spectrum of
biological functions including neurotransmitter, neurotrophic and neuroprotective. Moreover …
biological functions including neurotransmitter, neurotrophic and neuroprotective. Moreover …
Association of pituitary adenylate cyclase–activating polypeptide with cognitive decline in mild cognitive impairment due to Alzheimer disease
Importance There is a deficit of pituitary adenylate cyclase–activating polypeptide (PACAP)
in patients with neuropathologically confirmed Alzheimer dementia. However, whether this …
in patients with neuropathologically confirmed Alzheimer dementia. However, whether this …
Primary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengers
K Pal, S Mukhopadhyay - Developmental neurobiology, 2015 - Wiley Online Library
The ventral neural tube in vertebrates is patterned by a gradient of sonic hedgehog (Shh)
secreted from the notochord and floor plate. Forward genetic screens first pointed to the role …
secreted from the notochord and floor plate. Forward genetic screens first pointed to the role …
[HTML][HTML] Human mesenchymal stem/stromal cells suppress spinal inflammation in mice with contribution of pituitary adenylate cyclase-activating polypeptide (PACAP)
Background Adult human mesenchymal stem/stromal cells (hMSCs) from bone marrow have
been reported to exhibit beneficial effects on spinal cord injury (SCI). A neuropeptide …
been reported to exhibit beneficial effects on spinal cord injury (SCI). A neuropeptide …
PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin
JP Vu, D Goyal, L Luong, S Oh… - American Journal …, 2015 - journals.physiology.org
Pituitary adenylate cyclase-activating peptide (PACAP) is expressed within the gastroenteric
system, where it has profound physiological effects. PACAP was shown to regulate food …
system, where it has profound physiological effects. PACAP was shown to regulate food …