[HTML][HTML] Asparaginase therapy in pediatric acute lymphoblastic leukemia: a focus on the mode of drug resistance
SH Chen - Pediatrics & Neonatology, 2015 - Elsevier
Asparaginase is one of the most important chemotherapeutic agents against pediatric acute
lymphoblastic leukemia (ALL), the most common form of childhood cancer. The therapeutic …
lymphoblastic leukemia (ALL), the most common form of childhood cancer. The therapeutic …
Polymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia
M Ben Tanfous, B Sharif-Askari, F Ceppi, H Laaribi… - Clinical Cancer …, 2015 - AACR
Abstract Purpose: Asparaginase (ASNase) is a standard and critical component in the
therapy of childhood acute lymphoblastic leukemia (ALL), but it is also associated with …
therapy of childhood acute lymphoblastic leukemia (ALL), but it is also associated with …
Evaluating the Role of Admixture in Cancer Therapy Via in Vitro Drug Response and Multivariate Genome-Wide Associations
Aim: We investigate the role of ethnicity and admixture in drug response across a broad
group of chemotherapeutic drugs. Also, we generate hypotheses on the genetic variants …
group of chemotherapeutic drugs. Also, we generate hypotheses on the genetic variants …
Identification of genetic variants or genes that are associated with Homoharringtonine (HHT) response through a genome-wide association study in human …
Y Tong, N Niu, G Jenkins, A Batzler, L Li… - Frontiers in …, 2015 - frontiersin.org
Homoharringtonine (HHT) has been widely used in China to treat patients with acute and
chronic myeloid leukemia for decades. Since response to HHT varies among patients, our …
chronic myeloid leukemia for decades. Since response to HHT varies among patients, our …
Cell lines and animal model in the analysis of pharmacogenomics markers in childhood acute lymphoblastic leukemia
B Sharif Askari - 2015 - papyrus.bib.umontreal.ca
Acute lymphoblastic leukemia (ALL) is the most frequent malignancy of childhood. It is the
principal cause of cancer–related mortality in children due to a persistent group of patients …
principal cause of cancer–related mortality in children due to a persistent group of patients …