Seizure‐induced oxidative stress in temporal lobe epilepsy

S Puttachary, S Sharma, S Stark… - BioMed research …, 2015 - Wiley Online Library
An insult to the brain (such as the first seizure) causes excitotoxicity, neuroinflammation, and
production of reactive oxygen/nitrogen species (ROS/RNS). ROS and RNS produced during …

Overview of Nrf2 as therapeutic target in epilepsy

L Carmona-Aparicio, C Pérez-Cruz… - International journal of …, 2015 - mdpi.com
Oxidative stress is a biochemical state of imbalance in the production of reactive oxygen and
nitrogen species and antioxidant defenses. It is involved in the physiopathology of …

Clozapine linked to nanocapsules minimizes tissue and oxidative damage to biomolecules lipids, proteins and DNA in brain of rats Wistar

AA da Costa Güllich, RP Coelho, BC Pilar… - Metabolic Brain …, 2015 - Springer
Clozapine, atypical antipsychotic, can change oxidative stress parameters. It is known that
reactive species, in excess, can have a crucial role in the etiology of diseases, as well as …

Microglial ROS production in an electrical rat post-status epilepticus model of epileptogenesis

ML Rettenbeck, EL von Rüden, S Bienas, R Carlson… - Neuroscience …, 2015 - Elsevier
Reactive oxygen species and inflammatory signaling have been identified as pivotal
pathophysiological factors contributing to epileptogenesis. Considering the development of …

Avaliação do potencial anticonvulsivante do extrato padronizado de Justicia pectoralis (Chambá): estudo de neuroproteção e mecanismo de ação

ET Venâncio - 2015 - repositorio.ufc.br
Epilepsy affects about 50 million people and 30% of these people have refractory seizures
to the treatment available. The mechanism of seizure involves alteration in neurotransmitters …

Oral Administration of Methylphenidate Induces Hippocampal Necrosis in Juvenile Rats

N Banihabib, ME Haghi, MI Pour, S Zare… - Neurosurgery …, 2015 - journals.lww.com
Abstract Introduction: Methylphenidate (MPH: Ritalin) is a neural stimulant prescribed for the
treatment of attention-deficit/hyperactivity disorder. The recent neurochemical studies …