Objectives: To provide guidance for the management of mood disorders, based on scientific
evidence supplemented by expert clinical consensus and formulate recommendations to …

Introduction: Modest response and remission rates for the selective serotonin reuptake
inhibitors and the serotonin-norepinephrine reuptake inhibitors, coupled with mounting …

People with severe mental illness have a considerably shorter lifespan than the general
population. This excess mortality is mainly due to physical illness. Next to mental illness …

Background Treatment-resistant major depression is common and potentially life-
threatening in elderly people, in whom little is known about the benefits and risks of …

Background Overdose of amphetamine, related derivatives, and analogues (ARDA)
continues to be a serious worldwide health problem. Patients frequently present to the …

Objective To evaluate the effect of antipsychotics on the corrected QT (QTc) interval in youth.
Method We searched PubMed (http://www. ncbi. nlm. nih. gov/pubmed) for randomized or …

Neurocognitive impairment due to Alzheimer's disease (previously termed Alzheimer's
dementia)(AD) is the most common form of cognitive impairment worldwide. Given the …

Objectives The aim of this systematic review is to identify case reports of citalopram use
resulting in QTc prolongation, torsades de pointes, or both, in the medical literature. Methods …

The QT interval represents ventricular depolarisation and repolarisation. Prolongation of this
interval can lead to life-threatening complications. These can include arrhythmias such as …

Purpose Monitoring of the QT duration by electrocardiography (ECG) prior to treatment is
frequently recommended in the label of QT‐prolonging drugs. It is, however, unknown how …