Current trends in the etiology and diagnosis of HPV‐related head and neck cancers

RC Chai, D Lambie, M Verma… - Cancer medicine, 2015 - Wiley Online Library
Human papilloma virus (HPV) infection is a major risk factor for a distinct subset of head and
neck squamous cell carcinoma (HNSCC). The current review summarizes the epidemiology …

The application of virus-like particles as vaccines and biological vehicles

D Yan, YQ Wei, HC Guo, SQ Sun - Applied microbiology and …, 2015 - Springer
Virus-like particles (VLPs) can be spontaneously self-assembled by viral structural proteins
under appropriate conditions in vitro while excluding the genetic material and potential …

Structural and computational biology in the design of immunogenic vaccine antigens

L Liljeroos, E Malito, I Ferlenghi… - Journal of immunology …, 2015 - Wiley Online Library
Vaccination is historically one of the most important medical interventions for the prevention
of infectious disease. Previously, vaccines were typically made of rather crude mixtures of …

Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology

AF Rodrigues, HR Soares, MR Guerreiro… - Biotechnology …, 2015 - Wiley Online Library
Vaccination is one of the most effective interventions in global health. The worldwide
vaccination programs significantly reduced the number of deaths caused by infectious …

[HTML][HTML] From the monovalent to the nine-valent HPV vaccine

S Pils, EA Joura - Clinical Microbiology and Infection, 2015 - Elsevier
An investigational monovalent human papillomavirus (HPV) 16 virus-like particle vaccine
has been shown to prevent persistent infection and cervical disease related to HPV 16 and …

De novo design of an RNA tile that self-assembles into a homo-octameric nanoprism

J Yu, Z Liu, W Jiang, G Wang, C Mao - Nature communications, 2015 - nature.com
Rational, de novo design of RNA nanostructures can potentially integrate a wide array of
structural and functional diversities. Such nanostructures have great promises in biomedical …

A chimeric EBV gp350/220-based VLP replicates the virion B-cell attachment mechanism and elicits long-lasting neutralizing antibodies in mice

JG Ogembo, MR Muraswki, LW McGinnes… - Journal of translational …, 2015 - Springer
Abstract Epstein-Barr virus (EBV), an oncogenic gammaherpesvirus, causes acute infectious
mononucleosis (AIM) and is linked to the development of several human malignancies …

HPV vaccination for prevention of skin cancer

SE Vinzón, F Rösl - Human vaccines & immunotherapeutics, 2015 - Taylor & Francis
Cutaneous papillomaviruses are associated with specific skin diseases, such as extensive
wart formation and the development of non-melanoma skin cancer (NMSC), especially in …

Papillomavirus infectious pathways: a comparison of systems

J Biryukov, C Meyers - Viruses, 2015 - mdpi.com
The HPV viral lifecycle is tightly linked to the host cell differentiation, causing difficulty in
growing virions in culture. A system that bypasses the need for differentiating epithelium has …

Recent progress in vaccination against human papillomavirus‐mediated cervical cancer

SJ McKee, AS Bergot… - Reviews in medical …, 2015 - Wiley Online Library
It has been more than 7 years since the commercial introduction of highly successful
vaccines protecting against high‐risk human papillomavirus (HPV) subtypes and the …