More tricks with tetramers: a practical guide to staining T cells with peptide–MHC multimers

G Dolton, K Tungatt, A Lloyd, V Bianchi… - …, 2015 - Wiley Online Library
Analysis of antigen‐specific T‐cell populations by flow cytometry with peptide–MHC (pMHC)
multimers is now commonplace. These reagents allow the tracking and phenotyping of T …

The regulatory role of invariant NKT cells in tumor immunity

RM McEwen-Smith, M Salio, V Cerundolo - Cancer immunology research, 2015 - AACR
Invariant natural killer T (iNKT) cells are a unique population of T lymphocytes, which lie at
the interface between the innate and adaptive immune systems, and are important …

Natural killer T cells in liver injury, inflammation and cancer

H Wang, S Yin - Expert review of gastroenterology & hepatology, 2015 - Taylor & Francis
The liver is an organ that has the largest amount of natural killer T (NKT) cells, which play
critical roles in the pathogenesis of liver diseases. In this article, the authors summarize …

Activation of human T cells by CD 1 and self‐lipids

A de Jong - Immunological reviews, 2015 - Wiley Online Library
Over two decades ago, it was discovered that the human T‐cell repertoire contains T cells
that do not recognize peptide antigens in the context of MHC molecules but instead respond …

A subset of CD8αβ+ invariant NKT cells in a humanized mouse model

X Wen, S Kim, R Xiong, M Li, A Lawrenczyk… - The Journal of …, 2015 - journals.aai.org
Invariant NKT (iNKT) cells are unconventional innate-like T cells demonstrating potent
antitumor function in conventional mouse models. However, the iNKT cell ligands have had …

Bacterial vaccines with cell wall-associated ceramide-like glycolipids and uses thereof

SA Porcelli, MM Venkataswamy - US Patent 9,139,809, 2015 - Google Patents
The invention is directed compositions and methods related to bacterial cells physically
associated with ceramide-like glycolipids. The invention allows for delivery of ceramide like …

Genotype-associated differential NKG2D expression on CD56+ CD3+ lymphocytes predicts response to pegylated-interferon/ribavirin therapy in chronic hepatitis C

P Chu, H Ebinuma, N Nakamoto, K Sugiyama, S Usui… - PloS one, 2015 - journals.plos.org
Hepatitis C virus (HCV) genotype 1 infections are significantly more difficult to eradicate with
PEG-IFN/ribavirin therapy, compared to HCV genotype 2. The aim of this work is to …

[PDF][PDF] Invariant NKT Cells in

HM Model - researchgate.net
Invariant NKT (iNKT) cells are unconventional innate-like T cells demonstrating potent
antitumor function in conventional mouse models. However, the iNKT cell ligands have had …

NOVEL METHODS FOR MHC TETRAMER LIBRARY TECHNOLOGY

CAIL JOANNA - 2015 - scholarbank.nus.edu.sg
The ability to examine the status of T cells offers insights to the immune response against a
disease and contributes to the formulation of effective therapies or vaccines. MHC tetramers …

Vaccine composition for use against influenza

V Serra - US Patent 9,220,767, 2015 - Google Patents
US9220767B2 - Vaccine composition for use against influenza - Google Patents US9220767B2
- Vaccine composition for use against influenza - Google Patents Vaccine composition for use …