Safety of nanoparticles in medicine

J Wolfram, M Zhu, Y Yang, J Shen, E Gentile… - Current drug …, 2015 - ingentaconnect.com
Nanomedicine involves the use of nanoparticles for therapeutic and diagnostic purposes.
During the past two decades, a growing number of nanomedicines have received regulatory …

Gd-metallofullerenol nanomaterial as non-toxic breast cancer stem cell-specific inhibitor

Y Liu, C Chen, P Qian, X Lu, B Sun, X Zhang… - Nature …, 2015 - nature.com
The contemporary use of nanomedicines for cancer treatment has been largely limited to
serving as carriers for existing therapeutic agents. Here, we provide definitive evidence that …

Synchrotron radiation techniques for nanotoxicology

YF Li, J Zhao, Y Qu, Y Gao, Z Guo, Z Liu, Y Zhao… - … , Biology and Medicine, 2015 - Elsevier
Nanotoxicology studies the interactions of engineered nanomaterials with biological
systems. Traditional in vitro and in vivo toxicological assays have been successfully …

Gd–metallofullerenol nanomaterial suppresses pancreatic cancer metastasis by inhibiting the interaction of histone deacetylase 1 and metastasis-associated protein 1

Y Pan, L Wang, S Kang, Y Lu, Z Yang, T Huynh… - Acs Nano, 2015 - ACS Publications
The treatment of pancreatic cancer frequently fails due to local recurrence and hepatic
metastasis. Our previous study found that Gd@ C82 (OH) 22 can suppress pancreatic …

A highly efficient and tumor vascular-targeting therapeutic technique with size-expansible gadofullerene nanocrystals

M Zhen, C Shu, J Li, G Zhang, T Wang, Y Luo… - Science China …, 2015 - Springer
It has long been a dream to achieve tumor targeting therapy that can efficiently reduce the
toxicity and severe side effects of conventional antitumor chemotherapeutic agents. Taking …

Quantitative analysis of Gd@C82(OH)22 and cisplatin uptake in single cells by inductively coupled plasma mass spectrometry

LN Zheng, M Wang, LC Zhao, BY Sun, B Wang… - Analytical and …, 2015 - Springer
Cisplatin is a commonly used chemotherapeutic drug in cancer treatment, whereas Gd@ C
82 (OH) 22 is a new nanomaterial anti-tumor agent. In this study, we determined intracellular …

Oxidation-induced water-solubilization and chemical functionalization of fullerenes C 60, Gd@ C 60 and Gd@ C 82: atomistic insights into the formation mechanisms …

Z Wang, Z Lu, Y Zhao, X Gao - Nanoscale, 2015 - pubs.rsc.org
Water-solubilization is the prerequisite to endow the pristinely hydrophobic fullerenes with
biocompatibility and biofunctionality, which has been widely applied to derive fullerene …

[图书][B] Toxicology and risk assessment

AM Fan, G Alexeeff, E Khan - 2015 - books.google.com
The presence of chemicals in our environment is a subject of intense interest owing to the
many potential adverse health effects to humans following exposure to these chemicals. The …

Caging cancer

LP Balogh - Nanomedicine: Nanotechnology, Biology and Medicine, 2015 - Elsevier
This article summarizes the overall issues surrounding cancer for the general audience.
Individual differences between patients include genetic and non-genetic differences …

The isotopic effects of 13 C-labeled large carbon cage (C 70) fullerenes and their formation process

C Wang, L Ruan, XL Chang, X Zhang, ST Yang… - RSC Advances, 2015 - pubs.rsc.org
Fullerene, C60, and its derivatives, have been fully investigated and commercialized. The
importance of large carbon cage-based fullerenes for biomedical applications was gradually …