Migraine: multiple processes, complex pathophysiology
R Burstein, R Noseda, D Borsook - Journal of Neuroscience, 2015 - Soc Neuroscience
Migraine is a common, multifactorial, disabling, recurrent, hereditary neurovascular
headache disorder. It usually strikes sufferers a few times per year in childhood and then …
headache disorder. It usually strikes sufferers a few times per year in childhood and then …
Targeting CGRP: a new era for migraine treatment
S Wrobel Goldberg, SD Silberstein - CNS drugs, 2015 - Springer
Migraine is a highly prevalent headache disease that typically affects patients during their
most productive years. Despite significant progress in understanding the underlying …
most productive years. Despite significant progress in understanding the underlying …
CGRP as a neuropeptide in migraine: lessons from mice
AF Russo - British journal of clinical pharmacology, 2015 - Wiley Online Library
Migraine is a neurological disorder that is far more than just a bad headache. A hallmark of
migraine is altered sensory perception. A likely contributor to this altered perception is the …
migraine is altered sensory perception. A likely contributor to this altered perception is the …
[PDF][PDF] Slow internal dynamics and charge expansion in the disordered protein CGRP: A comparison with amylin
SM Sizemore, SM Cope, A Roy, G Ghirlanda… - Biophysical journal, 2015 - cell.com
We provide the first direct experimental comparison, to our knowledge, between the internal
dynamics of calcitonin-gene-related peptide (CGRP) and amylin (islet amyloid polypeptide …
dynamics of calcitonin-gene-related peptide (CGRP) and amylin (islet amyloid polypeptide …
[PDF][PDF] 降钙素基因相关肽在偏头痛中的作用
齐丹丹, 张芹, 张忠玲 - 国际神经病学神经外科学杂志, 2015 - jinn.org.cn
降钙素基因相关肽在偏头痛中的作用 Page 1 收稿日期: 2015 - 10 - 19; 修回日期: 2015 - 12 - 03
作者简介: 齐丹丹( 1988 - ) ,女,硕士,主要从事偏头痛和缺血性脑血管病的研究.E-mail …
作者简介: 齐丹丹( 1988 - ) ,女,硕士,主要从事偏头痛和缺血性脑血管病的研究.E-mail …
[HTML][HTML] Synergistic suppression of cortical spreading depression under NR2A and NR2B inhibition
Cortical spreading depression (CSD) is a transient synaptic excitation, followed by
depression, which can propagate slowly across cortex, subcortex and retina. CSD is …
depression, which can propagate slowly across cortex, subcortex and retina. CSD is …
Pathophysiology of migraine: current status and future directions
JM Hansen, D Levy - Pathophysiology of Headaches: From Molecule to …, 2015 - Springer
Around 10% of the global adult population has active migraine. The public health burden of
migraine is high because migraine attacks are associated with temporary disability and …
migraine is high because migraine attacks are associated with temporary disability and …
Peptide Agonists and Antagonists with Potential Application in Neurological Disorders
A Russo, SL Manna, G Morelli… - Recent Patents on …, 2015 - ingentaconnect.com
Background: Peptides are usually used to investigate regulatory networks and protein
function. They can also be used in therapeutic research: They are employed both to identify …
function. They can also be used in therapeutic research: They are employed both to identify …
[PDF][PDF] Exploring aspects of allosteric modulation and bias signalling at the glucagon-like peptide-1 receptor
EE Savage - 2015 - scholar.archive.org
The glucagon-like peptide-1 receptor (GLP-1R) is an important regulator of insulin
biosynthesis and secretion, and is one of the key therapeutic targets in the management of …
biosynthesis and secretion, and is one of the key therapeutic targets in the management of …