Antimicrobial activity of oleanolic and ursolic acids: an update

JA Jesus, JHG Lago, MD Laurenti… - Evidence‐Based …, 2015 - Wiley Online Library
Triterpenoids are the most representative group of phytochemicals, as they comprise more
than 20,000 recognized molecules. These compounds are biosynthesized in plants via …

The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental …

ES Yamamoto, BLS Campos, JA Jesus, MD Laurenti… - PLoS …, 2015 - journals.plos.org
Among neglected tropical diseases, leishmaniasis is one of the most important ones,
affecting more than 12 million people worldwide. The available treatments are not well …

A lupane-triterpene isolated from Combretum leprosum Mart. fruit extracts that interferes with the intracellular development of Leishmania (L.) amazonensis in vitro

CBG Teles, LS Moreira-Dill, AA Silva… - … and Alternative Medicine, 2015 - Springer
Abstract Background 3beta, 6beta, 16beta-trihydroxylup-20 (29)-ene is a lupane triterpene
isolated from Combretum leprosum fruit. The lupane group has been extensively used in …

In vitro antibacterial and chemical properties of essential oils including native plants from Brazil against pathogenic and resistant bacteria

LN Barbosa, I da Silva Probst, BFMT Andrade… - Journal of oleo …, 2015 - jstage.jst.go.jp
The antimicrobials products from plants have increased in importance due to the therapeutic
potential in the treatment of infectious diseases. Therefore, we aimed to examine the …

Natural products as inhibitors of recombinant cathepsin L of Leishmania mexicana

LRF de Sousa, H Wu, L Nebo, JB Fernandes… - Experimental …, 2015 - Elsevier
Cysteine proteinases (cathepsins) from Leishmania spp. are promising molecular targets
against leishmaniasis. Leishmania mexicana cathepsin L is essential in the parasite life …

[HTML][HTML] Chemical constituents from Sidastrum paniculatum and evaluation of their leishmanicidal activity

YCF Teles, OS Chaves, MF Agra, LM Batista… - Revista Brasileira de …, 2015 - SciELO Brasil
Abstract Sidastrum paniculatum (L.) Fryxell, Malvaceae, is popularly known in Brazil as
“malva-roxa” or “malvavisco”. The species is found mainly in Northeast region where it is …

QSAR-guided semi-synthesis and in vitro validation of antiplasmodial activity in ursolic acid derivatives

K Kalani, HS Cheema, H Tripathi, F Khan… - RSC …, 2015 - pubs.rsc.org
As a part of our antimalarial drug discovery programme, a quantitative structure–activity
relationship (QSAR) model was developed for the prediction of antiplasmodial activity in …

Cytotoxic activity of isolated constituents from leaves of Premna serratifolia on MCF-7 and HT-29 cell lines

M Biradi, K Hullatti - ||| Bangladesh Journal of Pharmacology|||, 2015 - bdpsjournal.org
Abstract Premna serratifolia (Syn: Premna integrifolia) is an important medicinal herb known
as †œAgnimantha†in Ayurveda and traditionally used for anticancer activity. The …

[PDF][PDF] Therapeutic Arsenal against Leishmaniases: A Review

JB de Menezes, TA da Silva, LAM Grillo, CB Dornelas - 2015 - academia.edu
Leishmaniases are included in the group of reemerging neglected tropical diseases caused
by flagellated parasites of the Leishmania genus. WHO recommends the use of …