Aging and multimorbidity: new tasks, priorities, and frontiers for integrated gerontological and clinical research

E Fabbri, M Zoli, M Gonzalez-Freire, ME Salive… - Journal of the American …, 2015 - Elsevier
Aging is characterized by rising susceptibility to development of multiple chronic diseases
and, therefore, represents the major risk factor for multimorbidity. From a gerontological …

Multimorbidity and functional decline in community-dwelling adults: a systematic review

A Ryan, E Wallace, P O'Hara, SM Smith - Health and quality of life …, 2015 - Springer
Background Multimorbidity affects up to one quarter of primary care populations. It is
associated with reduced quality of life, an increased risk of mental health difficulties and …

The increasing burden and complexity of multimorbidity

AJ Koné Pefoyo, SE Bronskill, A Gruneir, A Calzavara… - BMC public health, 2015 - Springer
Background Multimorbidity, the co-occurrence of two or more chronic conditions, is common
among older adults and is known to be associated with high costs and gaps in quality of …

The impact of multimorbidity on adult physical and mental health in low-and middle-income countries: what does the study on global ageing and adult health (SAGE) …

P Arokiasamy, U Uttamacharya, K Jain, RB Biritwum… - BMC medicine, 2015 - Springer
Background Chronic diseases contribute a large share of disease burden in low-and middle-
income countries (LMICs). Chronic diseases have a tendency to occur simultaneously and …

Mental health in Dutch adolescents: a TRAILS report on prevalence, severity, age of onset, continuity and co-morbidity of DSM disorders

J Ormel, D Raven, F van Oort, CA Hartman… - Psychological …, 2015 - cambridge.org
BackgroundWith psychopathology rising during adolescence and evidence suggesting that
adult mental health burden is often due to disorders beginning in youth, it is important to …

Risk of developing multimorbidity across all ages in an historical cohort study: differences by sex and ethnicity

JL St Sauver, CM Boyd, BR Grossardt, WV Bobo… - BMJ open, 2015 - bmjopen.bmj.com
Objective To study the incidence of de novo multimorbidity across all ages in a
geographically defined population with an emphasis on sex and ethnic differences. Design …

The structure of psychopathology in adolescence: Replication of a general psychopathology factor in the TRAILS study

OM Laceulle, WAM Vollebergh… - Clinical Psychological …, 2015 - journals.sagepub.com
This study aimed to replicate a study by Caspi and colleagues, which proposed that the
structure of psychopathology is characterized by a general psychopathology factor, in …

Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers

E Fabbri, Y An, M Zoli, EM Simonsick… - … Series A: Biomedical …, 2015 - academic.oup.com
Background. Multimorbidity increases with aging, but risk factors beyond age are unknown.
Objective. To investigate the association of inflammatory and anabolic hormonal biomarkers …

Syndemics of psychosocial problems and HIV risk: A systematic review of empirical tests of the disease interaction concept

AC Tsai, BFO Burns - Social Science & Medicine, 2015 - Elsevier
In the theory of syndemics, diseases co-occur in particular temporal or geographical
contexts due to harmful social conditions (disease concentration) and interact at the level of …

Effectiveness of case management for'at risk'patients in primary care: a systematic review and meta-analysis

J Stokes, M Panagioti, R Alam, K Checkland… - PloS one, 2015 - journals.plos.org
Background An ageing population with multimorbidity is putting pressure on health systems.
A popular method of managing this pressure is identification of patients in primary care 'at …