Understanding the mysterious M2 macrophage through activation markers and effector mechanisms
T Rőszer - Mediators of inflammation, 2015 - Wiley Online Library
The alternatively activated or M2 macrophages are immune cells with high phenotypic
heterogeneity and are governing functions at the interface of immunity, tissue homeostasis …
heterogeneity and are governing functions at the interface of immunity, tissue homeostasis …
Microglial and macrophage polarization—new prospects for brain repair
The traditional view of the adult brain as a static organ has changed in the past three
decades, with the emergence of evidence that it remains plastic and has some regenerative …
decades, with the emergence of evidence that it remains plastic and has some regenerative …
Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains
DG Walker, LF Lue - Alzheimer's research & therapy, 2015 - Springer
Inflammatory responses in the brain, which can be demonstrated by changes in properties of
microglia, the brain-resident macrophages, are a common feature of human …
microglia, the brain-resident macrophages, are a common feature of human …
Roles of microglia in brain development, tissue maintenance and repair
The emerging roles of microglia are currently being investigated in the healthy and diseased
brain with a growing interest in their diverse functions. In recent years, it has been …
brain with a growing interest in their diverse functions. In recent years, it has been …
TREM2 regulates microglial cell activation in response to demyelination in vivo
C Cantoni, B Bollman, D Licastro, M Xie, R Mikesell… - Acta …, 2015 - Springer
Microglia are phagocytic cells that survey the brain and perform neuroprotective functions in
response to tissue damage, but their activating receptors are largely unknown. Triggering …
response to tissue damage, but their activating receptors are largely unknown. Triggering …
[HTML][HTML] The role of microglia and myeloid immune cells in acute cerebral ischemia
The immune response to acute cerebral ischemia is a major contributor to stroke
pathobiology. The inflammatory response is characterized by the participation of brain …
pathobiology. The inflammatory response is characterized by the participation of brain …
M1 and M2 immune activation in Parkinson's disease: foe and ally?
Parkinson's Disease (PD) is a chronic and progressive neurodegenerative disorder of
unknown etiology. Autopsy findings, genetics, retrospective studies, and molecular imaging …
unknown etiology. Autopsy findings, genetics, retrospective studies, and molecular imaging …
The “sweet” side of the protein corona: effects of glycosylation on nanoparticle–cell interactions
S Wan, PM Kelly, E Mahon, H Stockmann, PM Rudd… - ACS …, 2015 - ACS Publications
The significance of a protein corona on nanoparticles in modulating particle properties and
their biological interactions has been widely acknowledged. The protein corona is derived …
their biological interactions has been widely acknowledged. The protein corona is derived …
Effects of microglia on neurogenesis
K Sato - Glia, 2015 - Wiley Online Library
This review summarizes and organizes the literature concerning the effects of microglia on
neurogenesis, particularly focusing on the subgranular zone (SGZ) of the hippocampus and …
neurogenesis, particularly focusing on the subgranular zone (SGZ) of the hippocampus and …
Multiple sclerosis and T lymphocytes: an entangled story
L Legroux, N Arbour - Journal of Neuroimmune Pharmacology, 2015 - Springer
Multiple sclerosis (MS) is the prototypic inflammatory disease of the central nervous system
(CNS) characterized by multifocal areas of demyelination, axonal damage, activation of glial …
(CNS) characterized by multifocal areas of demyelination, axonal damage, activation of glial …