In December 1983, a seminal paper appeared on the overexpression of human IFN-β in
insect cells with a genetically engineered baculovirus. The finding that baculoviruses …

Eukaryotic cell lines, including Chinese hamster ovary cells, yeast, and insect cells, are
invaluable hosts for the production of many recombinant proteins. With the advent of …

Anchorage‐dependent cell cultures are used for the production of viruses, viral vectors, and
vaccines, as well as for various cell therapies and tissue engineering applications. Most of …

Human embryonic stem cells (hESCs) have an enormous potential as a source for cell
replacement therapies, tissue engineering, and in vitro toxicology applications. The lack of …

Advances in mechanistic knowledge of human neurological disorders have been hindered
by the lack of adequate human in vitro models. Three-dimensional (3D) cellular models …

The potential of adherent Madin Darby Canine Kidney (MDCK) cells for the production of
influenza viruses and canine adenovirus type 2 (CAV-2) for vaccines or gene therapy …

Recombinant adenovirus vectors (AdVs) have been used for the development of vaccines,
as gene therapy vectors and for protein production. Currently, the production of clinical …

Rubrivivax gelatinosus cultivated in wastewater environment can combine the biomass
resource recycling for generating chemicals with sewage purification. However, low biomass …

Folding of influenza virus hemagglutinin (HA) in the endoplasmic reticulum has been well
defined in mammalian cells. In different mammalian cell lines the protein follows the same …

The current master thesis was performed at the Animal Cell Technology Unit (ACTU),
IBET/ITQBNOVA, within the scope of the projects “Probing adenovirus-host cell interactions …