BackgroundNumerous treatment guidelines recommend that long-term use of
benzodiazepines (BZD) should be avoided primarily due to development of tolerance and a …

Sedatives are widely prescribed for anxiety or insomnia and include benzodiazepines,
selective benzodiazepine receptor subtype agonists (z-drugs), and barbiturates. These …

Rationale: Despite substantial public interest, few recommendations on the promotion of
good sleep health exist to educate health care providers and the general public on the …

Introduction Previous observational studies have associated benzodiazepine use with an
increased risk of dementia. However, limitations in the study methods leave questions …

More than half a century after their discovery, benzodiazepines (BDZs) still represent one of
the largest and most widely prescribed groups of psychotropic compounds, not only in …

Background High-dose benzodiazepine (BZD) dependence is associated with a wide
variety of negative health consequences. Affected individuals are reported to suffer from …

Background Benzodiazepine withdrawal syndrome has been reported following attempts to
withdraw even from low or therapeutic doses and has been compared to barbiturate and …

With current hypnotic agents, next-day residual effects are a common problem. The purpose
of the present study was to evaluate the residual effects of the commercially available …

Objective We investigated quality of life (QOL) and work performance of hypnotics users,
and explored the factors associated with multiple hypnotics usage in shift work nurses …

This study aimed to investigate the prevalence of the dependence for benzodiazepine or
their agonist (BZDs) hypnotics, as well as factors associated with this dependence among …