Functional genomics of PCOS: from GWAS to molecular mechanisms
Polycystic ovary syndrome (PCOS) is a common endocrinopathy characterized by increased
ovarian androgen biosynthesis, anovulation, and infertility. PCOS has a strong heritable …
ovarian androgen biosynthesis, anovulation, and infertility. PCOS has a strong heritable …
[HTML][HTML] The Association between Polymorphism of INSR and Polycystic Ovary Syndrome: A Meta-Analysis
C Feng, PP Lv, TT Yu, M Jin, JM Shen, X Wang… - International journal of …, 2015 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common gynecological endocrine disorder.
The genetic background is believed to play a crucial role in the pathogenesis of PCOS. In …
The genetic background is believed to play a crucial role in the pathogenesis of PCOS. In …
Family association study between melatonin receptor gene polymorphisms and polycystic ovary syndrome in Han Chinese
X Song, X Sun, G Ma, Y Sun, Y Shi, Y Du… - European Journal of …, 2015 - Elsevier
Objective The melatonin receptor (MTNR) gene, reported to be associated with insulin
sensitivity, diabetes and metabolic syndrome, could be a plausible candidate gene for …
sensitivity, diabetes and metabolic syndrome, could be a plausible candidate gene for …
[HTML][HTML] Association of vitamin D receptor gene variants with polycystic ovary syndrome: A case control study
T Mahmoudi, K Majidzadeh-A, H Farahani… - International Journal …, 2015 - ncbi.nlm.nih.gov
Background: Vitamin D and insulin play an important role in susceptibility to polycystic ovary
syndrome (PCOS), and therefore vitamin D receptor (VDR), parathyroid hormone (PTH), and …
syndrome (PCOS), and therefore vitamin D receptor (VDR), parathyroid hormone (PTH), and …
[HTML][HTML] An association study between INSR/NsiI (rs2059806) and INSR/PmlI (rs1799817) SNPs in women with polycystic ovary syndrome from West Azerbaijan …
M Bagheri, I Abdi-Rad, N Hosseini-Jazani… - … of Reproduction & …, 2015 - ncbi.nlm.nih.gov
Background It has been demonstrated that insulin signaling pathway related genes have
important roles in polycystic ovary syndrome (PCOS) risk. The goal of present investigation …
important roles in polycystic ovary syndrome (PCOS) risk. The goal of present investigation …
[HTML][HTML] PON1 polymorphisms are associated with polycystic ovary syndrome susceptibility, related traits, and PON1 activity in Indian women with the syndrome
R Dadachanji, N Shaikh, S Khavale, A Patil, N Shah… - Fertility and sterility, 2015 - Elsevier
Objective To investigate the association of paraoxonase 1 (PON1) polymorphisms (L55M
and Q192R) with polycystic ovary syndrome (PCOS) susceptibility and its related traits in …
and Q192R) with polycystic ovary syndrome (PCOS) susceptibility and its related traits in …
Gene polymorphisms related to insulin resistance and gene–environment interaction in colorectal cancer risk
X Hu, F Feng, X Li, P Yuan, R Luan, J Yan… - Annals of human …, 2015 - Taylor & Francis
Background and aim: Insulin resistance (IR) is an established risk factor for colorectal cancer
(CRC) and both IR and CRC physiologically overlap. As such, this study explored the …
(CRC) and both IR and CRC physiologically overlap. As such, this study explored the …
[HTML][HTML] Association of insulin receptor H1085H C> T, insulin receptor substrate 1 G972R and insulin receptor substrate 2 1057G/A polymorphisms with refractory …
F Che, Q Fu, X Li, N Gao, F Qi, Z Sun, Y Du, M Li - Seizure, 2015 - Elsevier
Purpose Insulin/insulin receptor (INSR) signaling plays diverse roles in the central nervous
system, including regulation of blood glucose, synaptic plasticity, dendritic growth …
system, including regulation of blood glucose, synaptic plasticity, dendritic growth …
[HTML][HTML] Agregación familiar de causa genética en familiares de primer grado de mujeres con síndrome de ovarios poliquísticos
G Ovies Carballo, I Sardiñas Díaz… - Revista Cubana de …, 2015 - scielo.sld.cu
Introducción: la existencia de manifestaciones del síndrome de ovarios poliquísticos en
familiares de primer grado de pacientes con ese síndrome, ha permitido sospechar la …
familiares de primer grado de pacientes con ese síndrome, ha permitido sospechar la …
多囊卵巢综合征遗传学机制的研究进展
许媛媛， 李佳蕊 - 国际生殖健康/计划生育杂志, 2015 - cqvip.com
作为常见且复杂的育龄期女性生殖内分泌疾病, 多囊卵巢综合征(PCOS) 以持续性无排卵,
高雄激素血症和(或) 卵巢多囊性改变为主要临床特征, 而其发病机制至今尚不明晰. PCOS …
高雄激素血症和(或) 卵巢多囊性改变为主要临床特征, 而其发病机制至今尚不明晰. PCOS …