Peripartum cardiomyopathy: current management and future perspectives

D Hilfiker-Kleiner, A Haghikia, J Nonhoff… - European heart …, 2015 - academic.oup.com
Pregnancy is associated with marked physiological changes challenging the cardiovascular
system. Among the more severe pregnancy associated cardiovascular complications …

Molecular mechanisms of preeclampsia

T Hod, AS Cerdeira… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Preeclampsia is a pregnancy-specific disease characterized by new onset hypertension and
proteinuria after 20 wk of gestation. It is a leading cause of maternal and fetal morbidity and …

Clinical outcomes for peripartum cardiomyopathy in North America: results of the IPAC Study (Investigations of Pregnancy-Associated Cardiomyopathy)

DM McNamara, U Elkayam, R Alharethi, J Damp… - Journal of the American …, 2015 - jacc.org
Background: Peripartum cardiomyopathy (PPCM) remains a major cause of maternal
morbidity and mortality. Objectives: This study sought to prospectively evaluate recovery of …

Cardio-oncology: how new targeted cancer therapies and precision medicine can inform cardiovascular discovery

AM Bellinger, CL Arteaga, T Force, BD Humphreys… - Circulation, 2015 - Am Heart Assoc
Cardio-oncology (the cardiovascular care of cancer patients) has developed as a new
translational and clinical field based on the expanding repertoire of mechanism-based …

Systems biology approaches to adverse drug effects: the example of cardio-oncology

SA Brown, N Sandhu, J Herrmann - Nature Reviews Clinical Oncology, 2015 - nature.com
Increased awareness of the cardiovascular toxic effects of chemotherapy has led to the
emergence of cardio-oncology (or onco-cardiology), which focuses on screening, monitoring …

Update on the pathophysiological implications and clinical role of angiogenic factors in pregnancy

E Llurba, F Crispi, S Verlohren - Fetal diagnosis and therapy, 2015 - karger.com
Angiogenic markers are now being incorporated into clinical practice for the screening,
diagnosing, and monitoring of preeclampsia. Pregnancy requires both vasculogenesis and …

Exposure to experimental preeclampsia in mice enhances the vascular response to future injury

D Pruthi, EV Khankin, RM Blanton, M Aronovitz… - …, 2015 - Am Heart Assoc
Cardiovascular disease (CVD) remains the leading killer of women in developed nations.
One sex-specific risk factor is preeclampsia, a syndrome of hypertension and proteinuria that …

Molecular mechanisms of peripartum cardiomyopathy: a vascular/hormonal hypothesis

NA Bello, Z Arany - Trends in cardiovascular medicine, 2015 - Elsevier
Peripartum cardiomyopathy (PPCM) is characterized by the development of systolic heart
failure in the last month of pregnancy or within the first 5 months postpartum. The disease …

Evidence of autoantibodies against cardiac troponin I and sarcomeric myosin in peripartum cardiomyopathy

A Haghikia, Z Kaya, J Schwab, R Westenfeld… - Basic research in …, 2015 - Springer
Peripartum cardiomyopathy (PPCM) is a major cause of pregnancy-related maternal heart
failure that develops towards the end of pregnancy or in the months following delivery. In …

Federalist principles for healthcare data networks

KD Mandl, IS Kohane - Nature biotechnology, 2015 - nature.com
Federalist principles for healthcare data networks | Nature Biotechnology Skip to main content
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