Chronic obstructive pulmonary disease is mainly a smoking-related disorder and affects
millions of people worldwide, with a large effect on individual patients and society as a …

Although survival has improved significantly in recent years, prematurity remains a major
cause of infant and childhood mortality and morbidity. Preterm births (< 37 weeks of …

Neonatal chronic lung disease, ie, bronchopulmonary dysplasia, is characterized by
impaired pulmonary development resulting from the impact of different risk factors including …

Rapid growth and formation of new gas exchange units (alveogenesis) are hallmarks of the
perinatal lung. Bronchopulmonary dysplasia (BPD), common in very premature infants, is …

Rationale: While infants who are born extremely premature and develop bronchopulmonary
dysplasia (BPD) have impaired alveolar development and decreased pulmonary diffusion …

In rhesus macaques, previous studies have shown that episodic exposure to allergen alone
or combined with ozone inhalation during the first 6 months of life results in a condition with …

Most healthy children shrug off viral respiratory tract infections with little difficulty or
assistance and a full recovery is the norm. A small minority, in contrast, are left with serious …

Case history: A 40-year-old woman is newly diagnosed with COPD in the UK. The degree of
airflow obstruction appears severe for her age and smoking history. She does not have α1 …