A computational theory of hippocampal function, and tests of the theory: new developments

RP Kesner, ET Rolls - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
The aims of the paper are to update Rolls' quantitative computational theory of hippocampal
function and the predictions it makes about the different subregions (dentate gyrus, CA3 and …

Theta–gamma coupling in the entorhinal–hippocampal system

LL Colgin - Current opinion in neurobiology, 2015 - Elsevier
Highlights•Theta–gamma coupling supports memory processes in the entorhinal–
hippocampal network.•Theta-modulated slow gamma may promote memory retrieval.•Theta …

The relationship between gamma frequency and running speed differs for slow and fast gamma rhythms in freely behaving rats

C Zheng, KW Bieri, SG Trettel, LL Colgin - Hippocampus, 2015 - Wiley Online Library
In hippocampal area CA1 of rats, the frequency of gamma activity has been shown to
increase with running speed (Ahmed and Mehta, 2012). This finding suggests that different …

Phthalates and neurotoxic effects on hippocampal network plasticity

MR Holahan, CA Smith - Neurotoxicology, 2015 - Elsevier
Phthalates are synthetically derived chemicals used as plasticizers in a variety of common
household products. They are not chemically bound to plastic polymers and over time, easily …

Strain and sex differences in brain and behaviour of adult rats: Learning and memory, anxiety and volumetric estimates

RJ Keeley, C Bye, J Trow, RJ McDonald - Behavioural brain research, 2015 - Elsevier
Alterations in behaviour can arise through a number of factors, including strain and sex.
Here, we explored strain and sex differences between Long–Evans (LER) and Wistar (WR) …

VEGF can protect against blood brain barrier dysfunction, dendritic spine loss and spatial memory impairment in an experimental model of diabetes

SL Taylor, D Trudeau, B Arnold, J Wang, K Gerrow… - Neurobiology of …, 2015 - Elsevier
Clinical and experimental studies have shown a clear link between diabetes, vascular
dysfunction and cognitive impairment. However, the molecular underpinnings of this …

[HTML][HTML] Inhibition of PMCA activity by tau as a function of aging and Alzheimer's neuropathology

M Berrocal, I Corbacho, M Vazquez-Hernandez… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Ca 2+-ATPases are plasma membrane and intracellular membrane transporters that use the
energy of ATP hydrolysis to pump cytosolic Ca 2+ out of the cell (PMCA) or into internal …

Barriers to developing a valid rodent model of Alzheimer's disease: from behavioral analysis to etiological mechanisms

DC Gidyk, SH Deibel, NS Hong… - Frontiers in …, 2015 - frontiersin.org
Sporadic Alzheimer's disease (AD) is the most prevalent form of age-related dementia. As
such, great effort has been put forth to investigate the etiology, progression, and underlying …

The watermaze

RGM Morris - The Maze Book: Theories, Practice, and Protocols for …, 2015 - Springer
This chapter chronicles the personal account of the development and refinement of the
spatial navigation task, now known as the watermaze. The watermaze began at the Gatty …

[HTML][HTML] Multiple forms of metaplasticity at a single hippocampal synapse during late postnatal development

DG McHail, TC Dumas - Developmental cognitive neuroscience, 2015 - Elsevier
Metaplasticity refers to adjustment in the requirements for induction of synaptic plasticity
based on the prior history of activity. Numerous forms of developmental metaplasticity are …