Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1 …
Resveratrol (RES) has been shown to possess many pharmacological activities including
protective effect against liver damage induced by hepatotoxins. In the present study, the …
protective effect against liver damage induced by hepatotoxins. In the present study, the …
[HTML][HTML] Ginseng alleviates cyclophosphamide-induced hepatotoxicity via reversing disordered homeostasis of glutathione and bile acid
H Zhu, MH Long, J Wu, MM Wang, XY Li, H Shen… - Scientific reports, 2015 - nature.com
Cyclophosphamide (CP), a chemotherapeutic agent, is restricted due to its side effects,
especially hepatotoxicity. Ginseng has often been clinically used with CP in China, but …
especially hepatotoxicity. Ginseng has often been clinically used with CP in China, but …
Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration
Y Jiang, X Fan, Y Wang, P Chen, H Zeng… - Toxicological …, 2015 - academic.oup.com
Acetaminophen (APAP) overdose is the most frequent cause of drug-induced acute liver
failure. Schisandra sphenanthera is a traditional hepato-protective Chinese medicine and …
failure. Schisandra sphenanthera is a traditional hepato-protective Chinese medicine and …
Oleanolic acid attenuates obstructive cholestasis in bile duct-ligated mice, possibly via activation of NRF2-MRPs and FXR antagonism
P Chen, J Li, X Fan, H Zeng, R Deng, D Li… - European Journal of …, 2015 - Elsevier
Obstructive cholestasis is characterized by impairment of hepatic canalicular bile efflux and
there are no clinically effective drugs to cure except surgeries. Previously we revealed that …
there are no clinically effective drugs to cure except surgeries. Previously we revealed that …
[HTML][HTML] Oral administration of oleanolic acid, isolated from Swertia mussotii Franch, attenuates liver injury, inflammation, and cholestasis in bile duct-ligated rats
J Chai, X Du, S Chen, XC Feng, Y Cheng… - … Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Background & aims: Oleanolic acid is abundantly distributed in Swertia mussotii Franch, a
Chinese traditional herb for the treatment of jaundice. However, the hepatoprotective role of …
Chinese traditional herb for the treatment of jaundice. However, the hepatoprotective role of …
Interactions between transporters and herbal medicines/drugs: a focus on hepatoprotective compounds
A Zhang, Q Li, X He, D Si, C Liu - Current drug metabolism, 2015 - ingentaconnect.com
Many herbal medicines and drugs are available in the clinic as potent hepatoprotective
agents for the treatment of commonly occurring liver diseases. Recently, herbal medicines …
agents for the treatment of commonly occurring liver diseases. Recently, herbal medicines …
Hepato-Protective Effects of Schisandra Sphenanthera Extract against Lithocholic Acid-Induced Cholestasis in Mice are Associated With the Activation of PXR …
H Zeng, D Li, X Qin, P Chen, H Tan, X Zeng, X Li… - Drug Metabolism and …, 2015 - ASPET
We previously reported the ethanol extract of Schisandra sphenanthera (Wuzhi tablet, WZ)
significantly protects against acetaminophen-induced hepatoxicity. However, whether it …
significantly protects against acetaminophen-induced hepatoxicity. However, whether it …