Nongenetic inheritance and transgenerational epigenetics

M Szyf - Trends in molecular medicine, 2015 - cell.com
The idea that inherited genotypes define phenotypes has been paramount in modern
biology. The question remains, however, whether stable phenotypes could be also inherited …

Can we observe epigenetic effects on human brain function?

YS Nikolova, AR Hariri - Trends in cognitive sciences, 2015 - cell.com
Imaging genetics has identified many contributions of DNA sequence variation to individual
differences in brain function, behavior, and risk for psychopathology. Recent studies have …

CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer

M Zauri, G Berridge, ML Thézénas, KM Pugh, R Goldin… - Nature, 2015 - nature.com
Cells require nucleotides to support DNA replication and repair damaged DNA. In addition
to de novo synthesis, cells recycle nucleotides from the DNA of dying cells or from cellular …

Crystal structure of human DNA methyltransferase 1

ZM Zhang, S Liu, K Lin, Y Luo, JJ Perry, Y Wang… - Journal of molecular …, 2015 - Elsevier
Abstract DNMT1 (DNA methyltransferase 1) is responsible for propagating the DNA
methylation patterns during DNA replication. DNMT1 contains, in addition to a C-terminal …

Epigenetics, a key for unlocking complex CNS disorders? Therapeutic implications

M Szyf - European Neuropsychopharmacology, 2015 - Elsevier
Aberrant changes in gene function are believed to be involved in a wide spectrum of human
disease including behavioral, cognitive and neurodegenerative pathologies. Most of the …

Structure and extent of DNA methylation-based epigenetic variation in wild emmer wheat (T. turgidum ssp. dicoccoides) populations

A Venetsky, A Levy-Zamir, V Khasdan, K Domb… - BMC Plant …, 2015 - Springer
Background The genetic structure and differentiation of wild emmer wheat suggests that
genetic diversity is eco-geographically structured. However, very little is known about the …

Epigenetics and well-being: Optimal adaptation to the environment

M Szyf, M Pluess, M Pluess - Genetics of psychological well …, 2015 - books.google.com
Whether PWB is predetermined by our genes—the legacy of inherited sequence differences
between humans—or whether it is past experiences and physical and social environments …

Expression level and immunolocalization of de novo methyltransferase 3 protein (TuDNMT3) in adult females and males of the two-spotted spider mite, Tetranychus …

SX Yang, C Guo, YK Zhang, JT Sun… - Experimental and Applied …, 2015 - Springer
DNA methylation is an epigenetic mechanism for regulating developmental and other
important processes in eukaryotes. Several essential components of the DNA methylation …

[PDF][PDF] Si-Xia Yang, Chao Guo, Yan-Kai Zhang

JT Sun, XY Hong - researchgate.net
DNA methylation is an epigenetic mechanism for regulating developmental and other
important processes in eukaryotes. Several essential components of the DNA methylation …

[引用][C] Role of DNA methyltransferases in maintaining mammary stem/progenitor and cancer stem cells

R Pathania - 2015