The emerging roles of microglia are currently being investigated in the healthy and diseased
brain with a growing interest in their diverse functions. In recent years, it has been …

The 18-kDA translocator protein (TSPO) is consistently elevated in activated microglia of the
central nervous system (CNS) in response to a variety of insults as well as …

Although substantial evidence has established that microglia and astrocytes play a key role
in the establishment and maintenance of persistent pain in animal models, the role of glial …

Molecular imaging is an attractive technology widely used in clinical practice that greatly
enhances our understanding of the pathophysiology and treatment in central nervous …

Parkinson's disease (PD) is the second most common neurodegenerative disorder
worldwide, being characterized by the progressive loss of dopaminergic neurons in the …

Axon injury/loss, demyelination and inflammation are the primary pathologies in multiple
sclerosis lesions. Despite the prevailing notion that axon/neuron loss is the substrate of …

Objective To characterize the changes in microglial proinflammatory M1 and
antiinflammatory M2 marker expression during epileptogenesis in the chronic pilocarpine …

Purpose Neuroinflammation plays a critical role in various neuropathological conditions,
and hence there is renewed interest in the translocator protein (TSPO) as a biomarker of …

Fluorine-18 labelled N, N-diethyl-2-(2-[4-(2-fluoroethoxy) phenyl]-5, 7-dimethylpyrazolo [1, 5-
α] pyrimidine-3-yl) acetamide ([18F] DPA-714) binds to the 18-kDa translocator protein …

The most accurate predictor of the subsequent development of multiple sclerosis in clinically
isolated syndrome is the presence of lesions at magnetic resonance imaging. We used in …