Lung nodule and cancer detection in computed tomography screening

GD Rubin - Journal of thoracic imaging, 2015 - journals.lww.com
Fundamental to the diagnosis of lung cancer in computed tomography (CT) scans is the
detection and interpretation of lung nodules. As the capabilities of CT scanners have …

Lung cancer biomarkers

I Hoseok, JY Cho - Advances in clinical chemistry, 2015 - Elsevier
Lung cancer is the most frequently occurring cancer in the world and continually leads in
mortality among cancers. The overall 5-year survival rate for lung cancer has risen only …

Performance of Lung-RADS in the National Lung Screening Trial: a retrospective assessment

PF Pinsky, DS Gierada, W Black, R Munden… - Annals of internal …, 2015 - acpjournals.org
Background: Lung cancer screening with low-dose computed tomography (LDCT) has been
recommended, based primarily on the results of the NLST (National Lung Screening Trial) …

[HTML][HTML] Tumor spread through air spaces is an important pattern of invasion and impacts the frequency and location of recurrences after limited resection for small …

K Kadota, J Nitadori, CS Sima, H Ujiie, NP Rizk… - Journal of Thoracic …, 2015 - Elsevier
Introduction Tumor invasion in lung adenocarcinoma is defined as infiltration of stroma,
blood vessels, or pleura. Based on observation of tumor spread through air spaces (STAS) …

Automatic classification of pulmonary peri-fissural nodules in computed tomography using an ensemble of 2D views and a convolutional neural network out-of-the-box

F Ciompi, B de Hoop, SJ van Riel, K Chung… - Medical image …, 2015 - Elsevier
In this paper, we tackle the problem of automatic classification of pulmonary peri-fissural
nodules (PFNs). The classification problem is formulated as a machine learning approach …

Association of coronary artery calcification and mortality in the national lung screening trial: a comparison of three scoring methods

C Chiles, F Duan, GW Gladish, JG Ravenel… - Radiology, 2015 - pubs.rsna.org
Purpose To evaluate three coronary artery calcification (CAC) scoring methods to assess
risk of coronary heart disease (CHD) death and all-cause mortality in National Lung …

[HTML][HTML] ESR/ERS white paper on lung cancer screening

HU Kauczor, L Bonomo, M Gaga, K Nackaerts… - European …, 2015 - Springer
Lung cancer is the most frequently fatal cancer, with poor survival once the disease is
advanced. Annual low-dose computed tomography has shown a survival benefit in …

A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer

AL Kasinski, K Kelnar, C Stahlhut, E Orellana, J Zhao… - Oncogene, 2015 - nature.com
Targeted cancer therapies, although often effective, have limited utility owing to preexisting
primary or acquired secondary resistance. Consequently, agents are sometimes used in …

Primary care provider-delivered smoking cessation interventions and smoking cessation among participants in the National Lung Screening Trial

ER Park, IF Gareen, S Japuntich, I Lennes… - JAMA internal …, 2015 - jamanetwork.com
Importance The National Lung Screening Trial (NLST) found a reduction in lung cancer
mortality among participants screened with low-dose computed tomography vs chest …

Barriers to uptake among high-risk individuals declining participation in lung cancer screening: a mixed methods analysis of the UK Lung Cancer Screening (UKLS) …

N Ali, KJ Lifford, B Carter, F McRonald, G Yadegarfar… - BMJ open, 2015 - bmjopen.bmj.com
Objective The current study aimed to identify the barriers to participation among high-risk
individuals in the UK Lung Cancer Screening (UKLS) pilot trial. Setting The UKLS pilot trial …