Significance: The colonization of wounds by specific microbes or communities of microbes
may delay healing and/or lead to infection-related complication. Studies of wound …

Wound healing is impaired in diabetes, resulting in significant morbidity and mortality.
Neutrophils are the main leukocytes involved in the early phase of healing. As part of their …

The majority of chronic infections are associated with mono-or polymicrobial biofilms, having
a significant impact on the patients' quality of life and survival rates. Although the use of …

The skin represents the primary interface between the host and the environment. This organ
is also home to trillions of microorganisms that play an important role in tissue homeostasis …

The past two decades have been marked by a surge in research to understand the microbial
communities that live in association with the human body, in part stimulated by affordable …

The influence of the skin microbiota on host susceptibility to infectious agents is largely
unexplored. The skin harbors diverse bacterial species that may promote or antagonize the …

Individuals with spinal cord injury (SCI) are at increased risk for the development of pressure
ulcers. These chronic wounds are debilitating and contribute to prolonged hospitalization …

Significance: Humans are under constant bombardment by various stressors, including
psychological anxiety and physiologic injury. Understanding how these stress responses …

Chronic, non-healing wounds contribute significantly to the suffering of patients with co-
morbidities in the clinical population with mild to severely compromised immune systems …

Significance: Open fractures are fractures in which the bone has violated the skin and soft
tissue. Because of their severity, open fractures are associated with complications that can …