Isothermal amplification of nucleic acids
Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …
Cancer biomarker detection: recent achievements and challenges
L Wu, X Qu - Chemical Society Reviews, 2015 - pubs.rsc.org
The early detection of cancer can significantly reduce cancer mortality and saves lives. Thus,
a great deal of effort has been devoted to the exploration of new technologies to detect early …
a great deal of effort has been devoted to the exploration of new technologies to detect early …
Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation
CW Shields Iv, CD Reyes, GP López - Lab on a Chip, 2015 - pubs.rsc.org
Accurate and high throughput cell sorting is a critical enabling technology in molecular and
cellular biology, biotechnology, and medicine. While conventional methods can provide high …
cellular biology, biotechnology, and medicine. While conventional methods can provide high …
Transformable liquid-metal nanomedicine
To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …
(DDSs). However, the clinical application of inorganic formulations has often been hindered …
Nucleic acid aptamers in cancer research, diagnosis and therapy
Aptamers are single-stranded DNA or RNA oligomers, identified from a random sequence
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …
[HTML][HTML] Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells
Circulating tumor cells (CTCs) are cells shed from the primary tumor and metastatic sites,
and can be found at very low frequencies in the peripheral blood of cancer patients.[1] …
and can be found at very low frequencies in the peripheral blood of cancer patients.[1] …
An aptamer-functionalized chemomechanically modulated biomolecule catch-and-release system
The efficient extraction of (bio) molecules from fluid mixtures is vital for applications ranging
from target characterization in (bio) chemistry to environmental analysis and biomedical …
from target characterization in (bio) chemistry to environmental analysis and biomedical …
[HTML][HTML] DNA aptamer selected against pancreatic ductal adenocarcinoma for in vivo imaging and clinical tissue recognition
X Wu, Z Zhao, H Bai, T Fu, C Yang, X Hu, Q Liu… - Theranostics, 2015 - ncbi.nlm.nih.gov
In this work, we have developed a truncated DNA aptamer, termed XQ-2d, with high affinity
and specificity for pancreatic ductal adenocarcinoma (PDAC). Aptamer XQ-2d selectively …
and specificity for pancreatic ductal adenocarcinoma (PDAC). Aptamer XQ-2d selectively …
Target-induced nano-enzyme reactor mediated hole-trapping for high-throughput immunoassay based on a split-type photoelectrochemical detection strategy
J Zhuang, D Tang, W Lai, M Xu, D Tang - Analytical chemistry, 2015 - ACS Publications
Photoelectrochemical (PEC) detection is an emerging and promising analytical tool.
However, its actual application still faces some challenges like potential damage of …
However, its actual application still faces some challenges like potential damage of …
Microfluidic devices to enrich and isolate circulating tumor cells
Given the potential clinical impact of circulating tumor cells (CTCs) in blood as a clinical
biomarker for the diagnosis and prognosis of various cancers, a myriad of detection methods …
biomarker for the diagnosis and prognosis of various cancers, a myriad of detection methods …