Migraine is a neurological disorder that manifests as a debilitating headache associated
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …

Migraine is a neurological disorder that is far more than just a bad headache. A hallmark of
migraine is altered sensory perception. A likely contributor to this altered perception is the …

Pain caused by acute pulpitis (AP) is a common symptom in clinical settings. However, its
underlying mechanisms have largely remained unknown. Using AP model, we …

Background The trigeminal ganglion (TG) plays a central role in cranial pain. Administration
of complete Freund's adjuvant (CFA) into the temporomandibular joint (TMJ) elicits activation …

AIM: To determine the molecular mechanisms of Shugan decoction (SGD) in the regulation
of colonic motility and visceral hyperalgesia (VHL) in irritable bowel syndrome (IBS) …

Previously, our group has demonstrated that chronic paracetamol (APAP) treatment induces
alterations to the trigeminovascular nociceptive system in the cortical spreading depression …

It has been well established that neurogenic inflammation is one of the major pathological
processes underlying inflammatory pain, but there are few effective anti‐inflammatory drugs …

Hyperactivity of trigeminal sensory neurons is a major process to generate recurrent
headache, typical of migraine attacks. How physiological nociception is converted into …

Atherosclerosis consists in a progressive accumulation of atheromatous plaques in medium
and large caliber artery walls. Shear stress is generated by the friction of blood flow on the …

Les douleurs oculaires aiguës et chroniques sont parmi les plus invalidantes et les plus
difficiles à traiter. Elles touchent plus particulièrement la cornée, tissu le plus innervé et le …