It is increasingly evident that many of the genomic mutations in cancer reside inside regions
that do not encode proteins. However, these regions are often transcribed into long …

Long noncoding RNAs are emerging as key players in various fundamental biological
processes. We highlight the varied molecular mechanisms by which lncRNAs modulate …

Protein-coding genes account for only~ 2% of the human genome, whereas the vast majority
of transcripts are non-coding RNAs (ncRNAs) including long ncRNAs (lncRNAs). A growing …

While our understanding of the molecular mechanisms underlying cancer has significantly
improved, most of our knowledge focuses on protein-coding genes that make up a fraction of …

Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related
death worldwide, and the biology of this cancer remains poorly understood. Recent …

Background Mounting evidence indicates that long noncoding RNAs (lncRNAs) could play a
pivotal role in cancer biology. However, the overall biological role and clinical significance of …

Accumulating experimental studies have indicated that lncRNAs play important roles in
various critical biological process and their alterations and dysregulations have been …

LncRNAs have a critical role in the regulation of cellular processes such as cancer
progression and metastasis. In the present study, we confirmed that TUG1 was …

Recently, a novel class of transcripts, long noncoding RNAs (lncRNAs), is involved in
diseases including cancer. Here, we investigated the the role of lncRNA PANDAR in the …

Esophageal squamous cell carcinoma (ESCC) is one of the prevalent and deadly cancers
worldwide, especially in Eastern Asia. The prognosis of ESCC remains poor; thus, it is still …