Abstract The Toll/interleukin-1 receptor/resistance protein (TIR) domain is a protein–protein
interaction domain consisting of 125–200 residues, widely distributed in animals, plants and …

There is a close relationship between the human host and the intestinal microbiota, which is
an assortment of microorganisms, protecting the intestine against colonization by …

Background and purpose Angiotensin II is a vaso-constrictive peptide that regulates blood
pressure homeostasis. Even though the inflammatory effects of AngII in renal …

Kaposi's sarcoma-associated herpesvirus (KSHV) is a human gammaherpesvirus with latent
and lytic reactivation cycles. The mechanism by which KSHV evades the innate immune …

In the present study turmerone enriched curcuma oil (C. oil) obtained from Curcuma longa L.
was evaluated in lipopolysaccharide (LPS) induced inflammation in THP-1 human …

Objective. Helicobacter pylori (Hp) is recognized by TLR4 and TLR2 receptors, which trigger
the activation of genes involved in the host immune response. Thus, we evaluated the effect …

Abstract Myeloid differentiation factor 88 (MYD88), a key adapter protein in Toll-like receptor
signaling, affects the immune response and the formation of the dorsal–ventral axis. Here …

Introduction Odontoblasts play an important role in post-developmental control of
mineralization in response to external stimuli in the tooth. The present study investigated …

The tumor necrosis factor receptor-associated factor 6 (TRAF6) gene encodes a protein that
acts downstream of the Toll-like receptor (TLR) pathway. TLRs activate inflammatory …

Natural products play a dominant role in the discovery of leads to develop drugs for the
treatment of human diseases. In recent years, some bioactive polysaccharides isolated from …