Impacts of bioinformatics to medicinal chemistry
KC Chou - Medicinal chemistry, 2015 - ingentaconnect.com
Facing the explosive growth of biological sequence data, such as those of protein/peptide
and DNA/RNA, generated in the post-genomic age, many bioinformatical and mathematical …
and DNA/RNA, generated in the post-genomic age, many bioinformatical and mathematical …
The natural history of ADP-ribosyltransferases and the ADP-ribosylation system
Catalysis of NAD+-dependent ADP-ribosylation of proteins, nucleic acids, or small
molecules has evolved in at least three structurally unrelated superfamilies of enzymes …
molecules has evolved in at least three structurally unrelated superfamilies of enzymes …
CDD: NCBI's conserved domain database
A Marchler-Bauer, MK Derbyshire… - Nucleic acids …, 2015 - academic.oup.com
NCBI's CDD, the Conserved Domain Database, enters its 15th year as a public resource for
the annotation of proteins with the location of conserved domain footprints. Going forward …
the annotation of proteins with the location of conserved domain footprints. Going forward …
NCBI BLAST+ integrated into Galaxy
PJA Cock, JM Chilton, B Grüning, JE Johnson… - …, 2015 - academic.oup.com
Abstract Background The NCBI BLAST suite has become ubiquitous in modern molecular
biology and is used for small tasks such as checking capillary sequencing results of single …
biology and is used for small tasks such as checking capillary sequencing results of single …
iUbiq-Lys: prediction of lysine ubiquitination sites in proteins by extracting sequence evolution information via a gray system model
As one of the most important posttranslational modifications (PTMs), ubiquitination plays an
important role in regulating varieties of biological processes, such as signal transduction …
important role in regulating varieties of biological processes, such as signal transduction …
Identification of microRNA precursor with the degenerate K-tuple or Kmer strategy
The microRNA (miRNA), a small non-coding RNA molecule, plays an important role in
transcriptional and post-transcriptional regulation of gene expression. Its abnormal …
transcriptional and post-transcriptional regulation of gene expression. Its abnormal …
[HTML][HTML] The ocean sampling day consortium
A Kopf, M Bicak, R Kottmann, J Schnetzer, I Kostadinov… - Gigascience, 2015 - Springer
Abstract Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial
Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine …
Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine …
Diversity and dynamics of bacteriocins from human microbiome
Human commensal microbiota are an important determinant of health and disease of the
host. Different human body sites harbour different bacterial microbiota, bacterial …
host. Different human body sites harbour different bacterial microbiota, bacterial …
[HTML][HTML] The genome and transcriptome of the zoonotic hookworm Ancylostoma ceylanicum identify infection-specific gene families
EM Schwarz, Y Hu, I Antoshechkin, MM Miller… - Nature …, 2015 - nature.com
Hookworms infect over 400 million people, stunting and impoverishing them,,. Sequencing
hookworm genomes and finding which genes they express during infection should help in …
hookworm genomes and finding which genes they express during infection should help in …
[HTML][HTML] Genome sequence of African swine fever virus BA71, the virulent parental strain of the nonpathogenic and tissue-culture adapted BA71V
JM Rodríguez, LT Moreno, A Alejo, A Lacasta… - PloS one, 2015 - journals.plos.org
The strain BA71V has played a key role in African swine fever virus (ASFV) research. It was
the first genome sequenced, and remains the only genome completely determined. A large …
the first genome sequenced, and remains the only genome completely determined. A large …