Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi

L Brown, JM Wolf, R Prados-Rosales… - Nature Reviews …, 2015 - nature.com
Extracellular vesicles (EVs) are produced by all domains of life. In Gram-negative bacteria,
EVs are produced by the pinching off of the outer membrane; however, how EVs escape the …

The spectrum of fungi that infects humans

JR Köhler, A Casadevall… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Few among the millions of fungal species fulfill four basic conditions necessary to infect
humans: high temperature tolerance, ability to invade the human host, lysis and absorption …

Fungal melanin: what do we know about structure?

JD Nosanchuk, RE Stark, A Casadevall - Frontiers in microbiology, 2015 - frontiersin.org
The production of melanin significantly enhances the virulence of many important human
pathogenic fungi. Despite fungal melanin's importance in human disease, as well as …

Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans

G Vargas, JDB Rocha, DL Oliveira… - Cellular …, 2015 - Wiley Online Library
The release of extracellular vesicles (EV) by fungal organisms is considered an alternative
transport mechanism to trans‐cell wall passage of macromolecules. Previous studies have …

Extracellular vesicle-mediated export of fungal RNA

R Peres da Silva, R Puccia, ML Rodrigues… - Scientific reports, 2015 - nature.com
Extracellular vesicles (EVs) play an important role in the biology of various organisms,
including fungi, in which they are required for the trafficking of molecules across the cell wall …

Proteomics Unravels Extracellular Vesicles as Carriers of Classical Cytoplasmic Proteins in Candida albicans

A Gil-Bona, A Llama-Palacios, CM Parra… - Journal of proteome …, 2015 - ACS Publications
The commensal fungus Candida albicans secretes a considerable number of proteins and,
as in different fungal pathogens, extracellular vesicles (EVs) have also been observed. Our …

Extracellular vesicles including exosomes in cross kingdom regulation: a viewpoint from plant-fungal interactions

M Samuel, M Bleackley, M Anderson… - Frontiers in plant …, 2015 - frontiersin.org
Throughout evolution, plants and pathogenic fungi have been in a constant battle where
fungi have developed new mechanisms to infect plants while plants have co-evolved to …

Extracellular vesicles: role in inflammatory responses and potential uses in vaccination in cancer and infectious diseases

JH Campos, RP Soares, K Ribeiro… - Journal of …, 2015 - Wiley Online Library
Almost all cells and organisms release membrane structures containing proteins, lipids, and
nucleic acids called extracellular vesicles (EVs), which have a wide range of functions …

Lipid biosynthetic genes affect Candida albicans extracellular vesicle morphology, cargo, and immunostimulatory properties

JM Wolf, J Espadas, J Luque-Garcia, T Reynolds… - Eukaryotic …, 2015 - Am Soc Microbiol
Microbial secretion is integral for regulating cell homeostasis as well as releasing virulence
factors during infection. The genes encoding phosphatidylserine synthase (CHO1) and …

Extracellular vesicles from Paracoccidioides pathogenic species transport polysaccharide and expose ligands for DC-SIGN receptors

RP da Silva, C Heiss, I Black, P Azadi, JQ Gerlach… - Scientific reports, 2015 - nature.com
Extracellular vesicles (EVs) mediate non-conventional transport of molecules across the
fungal cell wall. We aimed at describing the carbohydrate composition and surface …